Compile Data Set for Download or QSAR
Report error Found 172 Enz. Inhib. hit(s) with all data for entry = 12634
TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716376BDBM716376(US20250034108, Example 28)
Affinity DataIC50: 700nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716375BDBM716375(US20250034108, Example 27)
Affinity DataIC50: 800nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716378BDBM716378(US20250034108, Example 29)
Affinity DataIC50: 800nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716379BDBM716379(US20250034108, Example 30)
Affinity DataIC50: 1.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716356BDBM716356(US20250034108, Example 10)
Affinity DataIC50: 1.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716374BDBM716374(US20250034108, Example Rac-27)
Affinity DataIC50: 1.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716380BDBM716380(US20250034108, Example 31)
Affinity DataIC50: 1.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716354BDBM716354(US20250034108, Example 8)
Affinity DataIC50: 1.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716353BDBM716353(US20250034108, Example 7)
Affinity DataIC50: 1.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716382BDBM716382(US20250034108, Example 33)
Affinity DataIC50: 1.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716387BDBM716387(US20250034108, Example 37)
Affinity DataIC50: 1.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716357BDBM716357(US20250034108, Example 11)
Affinity DataIC50: 1.70E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716373BDBM716373(US20250034108, Example 26)
Affinity DataIC50: 1.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716370BDBM716370(US20250034108, Example 24)
Affinity DataIC50: 2.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716383BDBM716383(US20250034108, Example 34)
Affinity DataIC50: 2.20E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716371BDBM716371(US20250034108, Example Rac-25)
Affinity DataIC50: 2.20E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716386BDBM716386(US20250034108, Example Rac-37)
Affinity DataIC50: 2.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716377BDBM716377(US20250034108, Example Rac-29)
Affinity DataIC50: 2.50E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716381BDBM716381(US20250034108, Example 32)
Affinity DataIC50: 2.70E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716362BDBM716362(US20250034108, Example 16)
Affinity DataIC50: 2.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716402BDBM716402(US20250034108, Example 52)
Affinity DataIC50: 2.90E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716377BDBM716377(US20250034108, Example Rac-29)
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716337BDBM716337(US20250034108, Example 1)
Affinity DataIC50: 3.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716376BDBM716376(US20250034108, Example 28)
Affinity DataIC50: 3.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716416BDBM716416(US20250034108, Example 62)
Affinity DataIC50: 3.40E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716414BDBM716414(US20250034108, Example Rac-61)
Affinity DataIC50: 3.40E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716412BDBM716412(US20250034108, Example 59)
Affinity DataIC50: 3.40E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716409BDBM716409(US20250034108, Example 57)
Affinity DataIC50: 3.60E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716336BDBM716336(US20250034108, Example Rac-1)
Affinity DataIC50: 3.60E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716385BDBM716385(US20250034108, Example 36)
Affinity DataIC50: 3.70E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716408BDBM716408(US20250034108, Example Rac-57)
Affinity DataIC50: 3.70E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716417BDBM716417(US20250034108, Example 63)
Affinity DataIC50: 3.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716397BDBM716397(US20250034108, Example 47)
Affinity DataIC50: 3.90E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716384BDBM716384(US20250034108, Example 35)
Affinity DataIC50: 4.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716360BDBM716360(US20250034108, Example 14)
Affinity DataIC50: 4.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716355BDBM716355(US20250034108, Example 9)
Affinity DataIC50: 4.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716375BDBM716375(US20250034108, Example 27)
Affinity DataIC50: 4.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716361BDBM716361(US20250034108, Example 15)
Affinity DataIC50: 4.10E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716358BDBM716358(US20250034108, Example 12)
Affinity DataIC50: 4.20E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716404BDBM716404(US20250034108, Example 54)
Affinity DataIC50: 4.20E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716359BDBM716359(US20250034108, Example 13)
Affinity DataIC50: 4.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716388BDBM716388(US20250034108, Example 38)
Affinity DataIC50: 4.30E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716389BDBM716389(US20250034108, Example 39)
Affinity DataIC50: 4.40E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716405BDBM716405(US20250034108, Example Rac-55)
Affinity DataIC50: 4.50E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716394BDBM716394(US20250034108, Example 44)
Affinity DataIC50: 4.60E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716347BDBM716347(US20250034108, Example 2)
Affinity DataIC50: 4.70E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716362BDBM716362(US20250034108, Example 16)
Affinity DataIC50: 4.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716428BDBM716428(US20250034108, Example 75)
Affinity DataIC50: 4.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716395BDBM716395(US20250034108, Example 45)
Affinity DataIC50: 4.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 716410BDBM716410(US20250034108, Example 58)
Affinity DataIC50: 5.00E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

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