Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 12645
TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717591BDBM717591(5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.190nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717590BDBM717590(N-(1'-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin...)
Affinity DataIC50: 0.260nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717582BDBM717582(1'-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-...)
Affinity DataIC50: 0.260nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717583BDBM717583(N-(1'-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin...)
Affinity DataIC50: 0.310nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717588BDBM717588(5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.330nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 684696BDBM684696(US20240228490, Example 29 | N-Cyclopropyl-1′...)
Affinity DataIC50: 0.360nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50602049BDBM50602049(CHEMBL5179882 | US20250034168, Compound 19)
Affinity DataIC50: 0.360nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717587BDBM717587(3-ethyl-7-((4-(2-methylimidazo[1,2-a]pyrazin-6-yl)...)
Affinity DataIC50: 0.410nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717586BDBM717586(1'-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-...)
Affinity DataIC50: 0.410nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50602047BDBM50602047(CHEMBL5173989 | US11802128, Example 14 | US2025003...)
Affinity DataIC50: 0.510nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 595701BDBM595701(US11591331, Example 8 | US20240228490, Example 1 |...)
Affinity DataIC50: 0.590nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717584BDBM717584(5-((1-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin...)
Affinity DataIC50: 0.660nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717592BDBM717592(3-ethyl-7-((4-(2-(trifluoromethyl)imidazo[1,2-a]py...)
Affinity DataIC50: 0.710nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50602045BDBM50602045(CHEMBL5193674 | US20250034168, Compound 8)
Affinity DataIC50: 0.780nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 684690BDBM684690(US20240228490, Example 2 | 5-(1-((7-Ethyl-6-oxo-5,...)
Affinity DataIC50: 0.790nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717574BDBM717574(5-(5-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.800nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717589BDBM717589(5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.950nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 717575BDBM717575(5-(8-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 1.60nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50602046BDBM50602046(CHEMBL5178741 | US20250034168, Compound 7 | US2025...)
Affinity DataIC50: 2.80nMAssay Description:PARP-1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and 25 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 595701BDBM595701(US11591331, Example 8 | US20240228490, Example 1 |...)
Affinity DataIC50: 31nMAssay Description:PARP2 and PARP7 chemical fluorescence detection kits were both purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 595701BDBM595701(US11591331, Example 8 | US20240228490, Example 1 |...)
Affinity DataIC50: 40nMAssay Description:PARP2 and PARP7 chemical fluorescence detection kits were both purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent