Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 12690
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720173BDBM720173(2-methyl-5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]...)
Affinity DataKi:  3.20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720189BDBM720189(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  3.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720160BDBM720160(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  3.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720162BDBM720162(2-methyl-6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2...)
Affinity DataKi:  4.20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720169BDBM720169(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  4.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720163BDBM720163(2-cyclobutyl-6-{[5-methyl-3-(6-methylpyridin-3-yl)...)
Affinity DataKi:  4.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720168BDBM720168(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  4.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720175BDBM720175(2-methyl-5-{5-methyl-4-[({7-methyl-5H,6H,7H,8H-pyr...)
Affinity DataKi:  5.60nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720187BDBM720187(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  5.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720172BDBM720172(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  6.60nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720182BDBM720182(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  7.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720170BDBM720170(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  7.40nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720164BDBM720164(2-(cyclobutylmethyl)-6-{[5-methyl-3-(6-methylpyrid...)
Affinity DataKi:  7.40nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720183BDBM720183(6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl-1H...)
Affinity DataKi:  8.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720165BDBM720165(2-cyclopentyl-6-{[5-methyl-3-(6-methylpyridin-3-yl...)
Affinity DataKi:  8.40nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720167BDBM720167(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  11.2nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720177BDBM720177(5-[5-methyl-4-({[7-(oxolan-3-yl)-5H,6H,7H,8H-pyrid...)
Affinity DataKi:  12.7nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720174BDBM720174(5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]pyridazin...)
Affinity DataKi:  17.1nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720176BDBM720176(5-[5-methyl-4-({5H,6H,7H,8H-pyrido[3,4-c]pyridazin...)
Affinity DataKi:  17.6nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720202BDBM720202(2-(3-ethyloxetan-3-yl)-6-{[4-methyl-1-(6-methylpyr...)
Affinity DataKi:  19nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720197BDBM720197(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  20.9nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720198BDBM720198(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  21.4nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720181BDBM720181(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  22.7nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720180BDBM720180(2-methyl-6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-...)
Affinity DataKi:  23nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720179BDBM720179(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  26.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720201BDBM720201(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  28nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720171BDBM720171(2-(1-methanesulfonylpropan-2-yl)-6-({5-methyl-3-[6...)
Affinity DataKi:  28.2nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720199BDBM720199(6-{[1-(6-methoxypyridin-3-yl)-4-methyl-1H-1,2,3-tr...)
Affinity DataKi:  28.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720166BDBM720166(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  29.3nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720192BDBM720192(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  29.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720188BDBM720188(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  29.7nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720178BDBM720178(3-{[3-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-y...)
Affinity DataKi:  35.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720190BDBM720190(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  36nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720161BDBM720161(6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  37nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720196BDBM720196(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  37.9nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720203BDBM720203(2-methyl-5-[4-methyl-5-({5H,6H,7H,8H-pyrido[3,4-c]...)
Affinity DataKi:  40.4nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720191BDBM720191(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  44.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720193BDBM720193(6-{[1-(6-methoxypyridin-3-yl)-4-methyl-1H-1,2,3-tr...)
Affinity DataKi:  51.6nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720195BDBM720195(3-{[6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-y...)
Affinity DataKi:  53.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720200BDBM720200(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-tri...)
Affinity DataKi:  61.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720205BDBM720205(5-{5-[({7-cyclobutyl-5H,6H,7H,8H-pyrido[3,4-c]pyri...)
Affinity DataKi:  61.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720186BDBM720186(2-methyl-6-({4-methyl-1-[6-(trifluoromethyl)pyridi...)
Affinity DataKi:  63.2nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720194BDBM720194(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  88.8nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720185BDBM720185(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  93.8nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720204BDBM720204(5-[5-({[7-(cyclobutylmethyl)-5H,6H,7H,8H-pyrido[3,...)
Affinity DataKi:  99.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Richter Gedeon

US Patent
LigandChemical structure of BindingDB Monomer ID 720184BDBM720184(6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl]-1...)
Affinity DataKi:  128nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent