Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 12710
TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 706753BDBM706753(mesembrine | US20240398759, Compound 001 | US20250...)
Affinity DataKi:  1.40nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50559715BDBM50559715(CHEMBL4781238 | US20250059156, Compound Mesembreno...)
Affinity DataKi:  27nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721503BDBM721503(US20250059156, Compound 117)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721518BDBM721518(US20250059156, Compound 218)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721502BDBM721502(US20250059156, Compound 118)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721499BDBM721499(US20250059156, Compound 110)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721500BDBM721500(US20250059156, Compound 111)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721511BDBM721511(US20250059156, Compound 120)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721491BDBM721491(US20250059156, Compound 102)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721507BDBM721507(US20250059156, Compound 209)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721524BDBM721524(US20250059156, Compound 224)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721489BDBM721489(US20250059156, Compound 115)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721521BDBM721521(US20250059156, Compound 221)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721490BDBM721490(US20250059156, Compound 103)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721517BDBM721517(US20250059156, Compound 216)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721501BDBM721501(US20250059156, Compound 208)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721516BDBM721516(US20250059156, Compound 215)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721509BDBM721509(US20250059156, Compound 203)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721519BDBM721519(US20250059156, Compound 219)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721520BDBM721520(US20250059156, Compound 220)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721515BDBM721515(US20250059156, Compound 214)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721497BDBM721497(US20250059156, Compound 108)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721498BDBM721498(US20250059156, Compound 109)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721512BDBM721512(US20250059156, Compound 121)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721493BDBM721493(US20250059156, Compound 104)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721494BDBM721494(US20250059156, Compound 105)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721510BDBM721510(US20250059156, Compound 204)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721508BDBM721508(US20250059156, Compound 210)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50559715BDBM50559715(CHEMBL4781238 | US20250059156, Compound Mesembreno...)
Affinity DataIC50: 470nMAssay Description:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution. Make only sufficient quantity needed for the assay; s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721495BDBM721495(US20250059156, Compound 106)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721525BDBM721525(US20250059156, Compound 227)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721523BDBM721523(US20250059156, Compound 226)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721492BDBM721492(US20250059156, Compound 116)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721504BDBM721504(US20250059156, Compound 201)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721513BDBM721513(US20250059156, Compound 122)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721514BDBM721514(US20250059156, Compound 213)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721496BDBM721496(US20250059156, Compound 107)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721505BDBM721505(US20250059156, Compound 206)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721522BDBM721522(US20250059156, Compound 223)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 721506BDBM721506(US20250059156, Compound 207)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sensorium Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 706753BDBM706753(mesembrine | US20240398759, Compound 001 | US20250...)
Affinity DataIC50: 7.80E+3nMAssay Description:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution. Make only sufficient quantity needed for the assay; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent