Compile Data Set for Download or QSAR
Report error Found 486 Enz. Inhib. hit(s) with all data for entry = 12758
TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725820BDBM725820(US20250074911, Example 43)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725820BDBM725820(US20250074911, Example 43)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725819BDBM725819(US20250074911, Example 42)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725819BDBM725819(US20250074911, Example 42)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725818BDBM725818(US20250074911, Example 41)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725818BDBM725818(US20250074911, Example 41)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725817BDBM725817(US20250074911, Example 40)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725817BDBM725817(US20250074911, Example 40)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725824BDBM725824(US20250074911, Example 47)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725824BDBM725824(US20250074911, Example 47)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725823BDBM725823(US20250074911, Example 46)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725823BDBM725823(US20250074911, Example 46)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725822BDBM725822(US20250074911, Example 45)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725822BDBM725822(US20250074911, Example 45)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725821BDBM725821(US20250074911, Example 44)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725821BDBM725821(US20250074911, Example 44)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725812BDBM725812(US20250074911, Example 35)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725812BDBM725812(US20250074911, Example 35)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725811BDBM725811(US20250074911, Example 34)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725811BDBM725811(US20250074911, Example 34)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725810BDBM725810(US20250074911, Example 33)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725810BDBM725810(US20250074911, Example 33)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725809BDBM725809(US20250074911, Example 32)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725809BDBM725809(US20250074911, Example 32)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725816BDBM725816(US20250074911, Example 39)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725816BDBM725816(US20250074911, Example 39)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725815BDBM725815(US20250074911, Example 38)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725815BDBM725815(US20250074911, Example 38)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725814BDBM725814(US20250074911, Example 37)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725814BDBM725814(US20250074911, Example 37)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725813BDBM725813(US20250074911, Example 36)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725813BDBM725813(US20250074911, Example 36)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725836BDBM725836(US20250074911, Example 59)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725836BDBM725836(US20250074911, Example 59)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725834BDBM725834(US20250074911, Example 57)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725834BDBM725834(US20250074911, Example 57)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725833BDBM725833(US20250074911, Example 56)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725833BDBM725833(US20250074911, Example 56)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725840BDBM725840(US20250074911, Example 63)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725840BDBM725840(US20250074911, Example 63)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725839BDBM725839(US20250074911, Example 62)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725839BDBM725839(US20250074911, Example 62)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725838BDBM725838(US20250074911, Example 61)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725838BDBM725838(US20250074911, Example 61)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725837BDBM725837(US20250074911, Example 60)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725837BDBM725837(US20250074911, Example 60)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725828BDBM725828(US20250074911, Example 51)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725828BDBM725828(US20250074911, Example 51)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725827BDBM725827(US20250074911, Example 50)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 725827BDBM725827(US20250074911, Example 50)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

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