Compile Data Set for Download or QSAR
Report error Found 212 Enz. Inhib. hit(s) with all data for entry = 12766
TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726498(6-chloro-5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6...)
Affinity DataIC50: 3nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726506(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 3nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726496(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726504(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726522(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726503(6-chloro-5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxal...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726501(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726515(6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726536(6-chloro-5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinox...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726523(6-chloro-5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxal...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726518(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726499(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726521(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726538(5-[4-[(2-ethyl-5-methyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726513(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726550(5-[4-[(2-cyclopropyl-5-fluoro-3-oxo-4H-quinoxalin-...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726520(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726537(5-[4-[(2-ethyl-5-methyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726500(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726519(6-(difluoromethyl)-5-[4-[(2-ethyl-5-fluoro-3-oxo-4...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726554(6-(difluoromethyl)-5-[4-[(2-methoxy-5-methyl-3-oxo...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726546(6-fluoro-5-[4-[(5-fluoro-2-isopropyl-3-oxo-4H-quin...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726540(N-ethyl-6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726517(6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726525(6-chloro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726502(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726534(6-fluoro-5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinox...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726512(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726526(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726516(6-(difluoromethyl)-5-[4-[(5-fluoro-2-methyl-3-oxo-...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726527(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726553(6-fluoro-5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinox...)
Affinity DataIC50: 8nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726551(5-[4-[(2-cyclopropyl-5-fluoro-3-oxo-4H-quinoxalin-...)
Affinity DataIC50: 8nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726508(6-fluoro-5-[4-[[5-fluoro-2-(1S)-1-fluoroethyl]-3-o...)
Affinity DataIC50: 9nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726541(N-ethyl-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxal...)
Affinity DataIC50: 10nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726511(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 10nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726535(5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726552(5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726497(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726510(5-[4-[[5-fluoro-2-[(1S)-1-fluoroethyl]-3-oxo-4H-qu...)
Affinity DataIC50: 12nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726533(5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 12nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726514(5-[4-[[2-(1,1-difluoroethyl)-5-fluoro-3-oxo-4H-qui...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726509(5-[4-[[5-fluoro-2-[(1R)-1-fluoroethyl]-3-oxo-4H-qu...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726505(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726507(6-fluoro-5-[4-[[5-fluoro-2-(1R)-1-fluoroethyl]-3-o...)
Affinity DataIC50: 15nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726524(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 15nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726531(6-fluoro-5-[4-[(5-fluoro-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 22nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726555(6-(difluoromethyl)-5-[4-[(2,5-dimethyl-3-oxo-4H-qu...)
Affinity DataIC50: 23nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726532(5-[4-[[2-(difluoromethyl)-5-fluoro-3-oxo-4H-quinox...)
Affinity DataIC50: 26nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726529(6-chloro-5-[4-[(5-fluoro-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 26nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

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