Compile Data Set for Download or QSAR
Report error Found 212 Enz. Inhib. hit(s) with all data for entry = 12766
TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726498BDBM726498(6-chloro-5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6...)
Affinity DataIC50: 3nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726506BDBM726506(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 3nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726496BDBM726496(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726504BDBM726504(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726522BDBM726522(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726503BDBM726503(6-chloro-5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxal...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726501BDBM726501(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726515BDBM726515(6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726536BDBM726536(6-chloro-5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinox...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726523BDBM726523(6-chloro-5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxal...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726518BDBM726518(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726499BDBM726499(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726521BDBM726521(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726538BDBM726538(5-[4-[(2-ethyl-5-methyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726513BDBM726513(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726550BDBM726550(5-[4-[(2-cyclopropyl-5-fluoro-3-oxo-4H-quinoxalin-...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726520BDBM726520(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726537BDBM726537(5-[4-[(2-ethyl-5-methyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726500BDBM726500(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726519BDBM726519(6-(difluoromethyl)-5-[4-[(2-ethyl-5-fluoro-3-oxo-4...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726554BDBM726554(6-(difluoromethyl)-5-[4-[(2-methoxy-5-methyl-3-oxo...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726546BDBM726546(6-fluoro-5-[4-[(5-fluoro-2-isopropyl-3-oxo-4H-quin...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726540BDBM726540(N-ethyl-6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726517BDBM726517(6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726525BDBM726525(6-chloro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxa...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726502BDBM726502(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726534BDBM726534(6-fluoro-5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinox...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726512BDBM726512(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 6nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726526BDBM726526(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726516BDBM726516(6-(difluoromethyl)-5-[4-[(5-fluoro-2-methyl-3-oxo-...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726527BDBM726527(5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 7nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726553BDBM726553(6-fluoro-5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinox...)
Affinity DataIC50: 8nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726551BDBM726551(5-[4-[(2-cyclopropyl-5-fluoro-3-oxo-4H-quinoxalin-...)
Affinity DataIC50: 8nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726508BDBM726508(6-fluoro-5-[4-[[5-fluoro-2-(1S)-1-fluoroethyl]-3-o...)
Affinity DataIC50: 9nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726541BDBM726541(N-ethyl-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxal...)
Affinity DataIC50: 10nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726511BDBM726511(5-[4-[(5-chloro-2-methyl-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 10nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726535BDBM726535(5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726552BDBM726552(5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726497BDBM726497(5-[4-[(2,5-dimethyl-3-oxo-4H-quinoxalin-6-yl)methy...)
Affinity DataIC50: 11nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726510BDBM726510(5-[4-[[5-fluoro-2-[(1S)-1-fluoroethyl]-3-oxo-4H-qu...)
Affinity DataIC50: 12nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726533BDBM726533(5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinoxalin-6-yl...)
Affinity DataIC50: 12nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726514BDBM726514(5-[4-[[2-(1,1-difluoroethyl)-5-fluoro-3-oxo-4H-qui...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726509BDBM726509(5-[4-[[5-fluoro-2-[(1R)-1-fluoroethyl]-3-oxo-4H-qu...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726505BDBM726505(5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726507BDBM726507(6-fluoro-5-[4-[[5-fluoro-2-(1R)-1-fluoroethyl]-3-o...)
Affinity DataIC50: 15nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726524BDBM726524(5-[4-[(2-ethyl-5-fluoro-3-oxo-4H-quinoxalin-6-yl)m...)
Affinity DataIC50: 15nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726531BDBM726531(6-fluoro-5-[4-[(5-fluoro-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 22nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726555BDBM726555(6-(difluoromethyl)-5-[4-[(2,5-dimethyl-3-oxo-4H-qu...)
Affinity DataIC50: 23nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726532BDBM726532(5-[4-[[2-(difluoromethyl)-5-fluoro-3-oxo-4H-quinox...)
Affinity DataIC50: 26nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726529BDBM726529(6-chloro-5-[4-[(5-fluoro-3-oxo-4H-quinoxalin-6-yl)...)
Affinity DataIC50: 26nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

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