Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 12780
TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728197BDBM728197(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4- di...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728166BDBM728166((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728195BDBM728195(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728194BDBM728194(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728191BDBM728191(2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728192BDBM728192(2-[(4-fluorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728174BDBM728174(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728169BDBM728169((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728170BDBM728170((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728167BDBM728167((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728181BDBM728181(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-[5- (c...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728179BDBM728179(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728180BDBM728180(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-[5-(et...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728209BDBM728209(2-[(4-methoxyphenyl) methyl]-2-azaspiro[3.3] hepta...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728178BDBM728178(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6R)-4-[5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728175BDBM728175(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728189BDBM728189(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728190BDBM728190(2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728188BDBM728188(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728185BDBM728185(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-2,5-d...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728183BDBM728183(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728184BDBM728184(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728196BDBM728196(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 2,6-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728193BDBM728193(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5,...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728205BDBM728205(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728206BDBM728206(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728203BDBM728203(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728171BDBM728171((2R)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-[...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728172BDBM728172((2R)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-[...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728168BDBM728168((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728182BDBM728182(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728177BDBM728177(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6R)-4-[5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728207BDBM728207(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728176BDBM728176(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-(5-met...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728208BDBM728208(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi:  300nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728198BDBM728198(2-benzyl-2-azaspiro [3.3]heptan-2-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728211BDBM728211(2-[(2-methoxyphenyl) methyl]-2-azaspiro[3.3] hepta...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728210BDBM728210(2-[(4-methylphenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728173BDBM728173((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728187BDBM728187(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-2,6-d...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728204BDBM728204(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728201BDBM728201(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728202BDBM728202(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-[5...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728186BDBM728186(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-2,6-d...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728199BDBM728199(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 728200BDBM728200(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMAssay Description:Binding affinity (Ki) for the compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M4 receptor. M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent