Compile Data Set for Download or QSAR
Report error Found 121 Enz. Inhib. hit(s) with all data for entry = 12804
TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729716((2R)-2-amino-3-(7-chloro-4-{[(furan- 2-yl)methyl]a...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729717(6-[(2S)-2-aminopropyl]-3-fluoro-7- methyl-N-[(thio...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729714((2R)-2-amino-3-(7-bromo-4- {[(thiophen-2- yl)methy...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729715((2R)-2-amino-3-(7-bromo-4-{[(furan- 2-yl)methyl]am...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729726(6-[(2R,3S)-2-amino-3-fluorobutyl]-7- methyl-N-[(th...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729631(6-[(2S)-2-aminopropyl]-7-methyl-N- [(thiophen-2-yl...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729660(6-[(2S)-2-aminopropyl]-7-bromo-N- [(thiophen-2-yl)...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729725(6-[(2S)-2-aminopropyl]-7-(prop-1-yn- 1-yl)-N-[(thi...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729661(6-[(2S)-2-aminopropyl]-7-chloro-N- [(thiophen-2-yl...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729720(6-[(2S)-2-aminopropyl]-7-bromo-N- [(furan-2-y1)met...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729721(6-[(2S)-2-aminopropyl]-7-chloro-N- [(furan-2-yl)me...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729732(6-[(2S)-2-aminopropyl]-7-ethynyl-N- [(thiophen-2-y...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729731(6-[(2S)-2-aminopropyl]-7-ethynyl-N- [(furan-2-y1)m...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729742(6-[(2R,3S)-2-amino-3-fluorobutyl]-7- bromo-N-[(thi...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729711((2R)-2-amino-3-(7-chloro-4- {[(thiophen-2- yl)meth...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729743(6-[(2R)-2-amino-3-methoxypropyl]-7- bromo-N-[(thio...)
Affinity DataIC50: 300nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729654((3S)-3-amino-4-(4-{[(furan-2- yl)methyl]amino}-7-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729655(6-[(2R)-2-amino-3- (methylsulfanyl)propyl]-N-[(fur...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729713(6-[2-amino-2-(oxetan-3-yl)ethyl]-7- methyl-N-[(thi...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729649(6-[(2S)-2-aminopropyl]-4-{[(thiophen- 2-yl)methyl]...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729727(6-[(2R,3R)-2-amino-3-fluorobutyl]-7- methyl-N-[(th...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729656(6-[(2S)-2-amino-4-fluorobutyl]-N- [(furan-2-yl)met...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729637(6-[(2S)-2-aminopropyl]-N-[(3- fluorothiophen-2-yl)...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729634((2R)-2-amino-3-(7-methyl-4- {[(thiophen-3- yl)meth...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729635(6-[(2S)-2-aminopropyl]-7-methyl-N- [(thiophen-3-yl...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729633(6-[(2S)-2-aminopropyl]-7-methyl-N- [(1,3-thiazol-2...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729647(6-[(2S)-2-aminopropyl]-7-methoxy-N- [(thiophen-2-y...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729704(6-[(2S)-2-aminopropyl]-7-cyclopropyl- N-[(thiophen...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729640(6-[(2S)-2-aminopropyl]-7-methyl-N- [(1H-pyrazol-1-...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729641(6-[(2S)-2-aminopropyl]-N-[(5- fluorothiophen-2-yl)...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729748(US20250101034, Compound 142)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729685((3S)-3-amino-4-(7-methyl-4- {[(thiophen-2- yl)meth...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729746(6-[(2S)-2-amino-1,1-difluoropropyl]-7- bromo-N-[(t...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729682(6-[(2R)-2-amino-3- (methylsulfanyl)propyl]-7-methy...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729747(6-(2-amino-3-fluoropropyl)-7-methyl- N-[(thiophen-...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729744(6-[(2R)-2-amino-3- cyclopropoxypropyl]-7-bromo-N- ...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729745(US20250101034, Compound 139)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729630((2R)-2-amino-3-(7-methyl-4- {[(thiophen-2- yl)meth...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729628((2R)-2-amino-3-(4-{[(furan-2- yl)methyl]amino}-7-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729692(6-[(2S)-2-amino-3-cyclopropylpropyl]- 7-methyl-N-[...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729629(6-[(2S)-2-aminopropyl]-N-[(furan-2- yl)methyl]-7-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729734(6-[(2S)-2-amino-1,1-difluoropropyl]-7- methyl-N-[(...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729670(6-[(2S)-2-aminopropyl]-N-[(4- fluorothiophen-2-yl)...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729664(6-[(2S)-2-aminopropyl]-N-[(thiophen- 2-yl)methyl]t...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729679(6-[(2S)-2-amino-1-fluoropropyl]-7- methyl-N-[(thio...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729676(6-[(2S)-2-amino-3-cyclopropylpropyl]- N-[(furan-2-...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729741(6-[(2R)-2-amino-3- (difluoromethoxy)propyl]-7-meth...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729677((2R)-2-amino-3-(4-{[(thiophen-2- yl)methyl]amino}t...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729738(6-[(2R)-2-amino-3-[(1R)-2,2- difluorocyclopropyl]p...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAtaxin-3(Mouse)
Skyhawk Therapeutics

US Patent
LigandPNGBDBM729674(6-[(2S)-2-amino-4,4,4-trifluorobutyl]- 7-methyl-N-...)
Affinity DataIC50: 2.75E+3nMAssay Description:ATXN3 protein levels were assessed by Mesoscale Discovery (MSD) assay developed with one pair of anti-ATXN3 antibodies. The capture and detect antibo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

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