Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 12819
TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM662984(Synthesis of 2,6-dimethoxy-N-(4-methoxy-6-(pyridin...)
Affinity DataIC50: 1nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730788(US20250122182, Example 45, WO2020/254946)
Affinity DataIC50: 1nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM663033(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Affinity DataIC50: 1nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM580748(US11492346, Example 90 | US20250122182, Example 98...)
Affinity DataIC50: 1nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730790(US20250122182, Syn. Ex. 14)
Affinity DataIC50: 2nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730781(US20250122182, Syn. Ex. 102)
Affinity DataIC50: 2nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM662998(Synthesis of 2,6-dimethoxy-N-(4-(pyridin-2-yloxy)-...)
Affinity DataIC50: 2nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730792(US20250122182, Syn. Ex. 25)
Affinity DataIC50: 2nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730783(US20250122182, Syn. Ex. 107)
Affinity DataIC50: 2nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730780(US20250122182, Syn. Ex. 101)
Affinity DataIC50: 4nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730791(US20250122182, Syn. Ex. 15)
Affinity DataIC50: 5nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730785(US20250122182, Syn. Ex. 52)
Affinity DataIC50: 12nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730789(US20250122182, Syn. Ex. 7)
Affinity DataIC50: 22nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730788(US20250122182, Example 45, WO2020/254946)
Affinity DataIC50: 24nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM663033(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Affinity DataIC50: 25.5nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM730786(US20250122182, Syn. Ex. 50)
Affinity DataIC50: 34nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM580748(US11492346, Example 90 | US20250122182, Example 98...)
Affinity DataIC50: 40nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM662998(Synthesis of 2,6-dimethoxy-N-(4-(pyridin-2-yloxy)-...)
Affinity DataIC50: 144nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM662984(Synthesis of 2,6-dimethoxy-N-(4-methoxy-6-(pyridin...)
Affinity DataIC50: 332nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730789(US20250122182, Syn. Ex. 7)
Affinity DataIC50: 571nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730792(US20250122182, Syn. Ex. 25)
Affinity DataIC50: 722nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730790(US20250122182, Syn. Ex. 14)
Affinity DataIC50: 878nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730791(US20250122182, Syn. Ex. 15)
Affinity DataIC50: 1.03E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730783(US20250122182, Syn. Ex. 107)
Affinity DataIC50: 1.63E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730786(US20250122182, Syn. Ex. 50)
Affinity DataIC50: 2.40E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730780(US20250122182, Syn. Ex. 101)
Affinity DataIC50: 2.49E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730781(US20250122182, Syn. Ex. 102)
Affinity DataIC50: 2.53E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM730785(US20250122182, Syn. Ex. 52)
Affinity DataIC50: 3.67E+3nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent