Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 12853
TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733681(N-((4-acrylamidocyclohexyl)methyl)-3-methoxy-4-((4...)
Affinity DataIC50: 0.900nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733706((R) 2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 0.970nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733677(N-(1-acryloylpiperidin-4-yl)-3-methoxy-4-((4-(((3-...)
Affinity DataIC50: 1.13nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733678(N-(1-acryloylpyrrolidin-3-yl)-3-methoxy-4-((4-(((3...)
Affinity DataIC50: 1.18nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733704((R)-2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.27nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733680(N-((1-acryloylpiperidin-4-yl)methyl)-3-methoxy-4-(...)
Affinity DataIC50: 1.32nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733708((S) 2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.35nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733705((S)-2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.45nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733679(N-(1-acryloyl piperidin-3-yl)-3-methoxy-4-((4-((3-...)
Affinity DataIC50: 1.59nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733682(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 2.68nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733699(2-((2-((4-(((3-(1-methylacryloyl piperidin-3-yl)ph...)
Affinity DataIC50: 2.93nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733689(2-(((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)a...)
Affinity DataIC50: 3.41nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733702((E)-2-((2-((4-(((3-(1-(but-2-enoyl)piperidin-3-yl)...)
Affinity DataIC50: 3.43nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733683(N-((1-acryloylpiperidin-4-yl)methyl)-4-((4-(2-(dim...)
Affinity DataIC50: 3.58nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733686(2-((2-((4-(((4-(1-acryloylpyrrolidin-2-yl)phenyl)a...)
Affinity DataIC50: 3.71nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733700(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 3.75nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733701(N-methyl-2-((2-((4-(((3-(1-propionylpiperidin-3-yl...)
Affinity DataIC50: 3.93nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733698(7-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 4.33nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733691(N-(3-(((2-((4-(((3-(N-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 4.36nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733697(7-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 4.98nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733703(2-((2-((4-(((3-(1-(2-fluoroacryloyl)piperidin-3-yl...)
Affinity DataIC50: 5.11nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733688(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 5.67nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733685((N-(1-acryloylpiperidin-4-yl)methyl)-4-((4-((2-(di...)
Affinity DataIC50: 5.79nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733694(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 6.13nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733693(2-((2-((4-(((3(1-acryloylpiperidin-3-yl)phenyl)ami...)
Affinity DataIC50: 6.73nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733692(2-(2-(4-((3-(1-aryloylpiperidin-3-yl)phenylamino)m...)
Affinity DataIC50: 7.84nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733696(2-((2-((4-(((3-(1-acryloylpiperidine-3-yl)phenyl)a...)
Affinity DataIC50: 10.4nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733687(1-(3-(3-((4-((4-((2-(dimethylphosphoryl)phenyl)ami...)
Affinity DataIC50: 15.8nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733695(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 17.9nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandPNGBDBM733690(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 19.8nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent