Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 12853
TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733681BDBM733681(N-((4-acrylamidocyclohexyl)methyl)-3-methoxy-4-((4...)
Affinity DataIC50: 0.900nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733706BDBM733706((R) 2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 0.970nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733677BDBM733677(N-(1-acryloylpiperidin-4-yl)-3-methoxy-4-((4-(((3-...)
Affinity DataIC50: 1.13nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733678BDBM733678(N-(1-acryloylpyrrolidin-3-yl)-3-methoxy-4-((4-(((3...)
Affinity DataIC50: 1.18nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733704BDBM733704((R)-2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.27nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733680BDBM733680(N-((1-acryloylpiperidin-4-yl)methyl)-3-methoxy-4-(...)
Affinity DataIC50: 1.32nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733708BDBM733708((S) 2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.35nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733705BDBM733705((S)-2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 1.45nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733679BDBM733679(N-(1-acryloyl piperidin-3-yl)-3-methoxy-4-((4-((3-...)
Affinity DataIC50: 1.59nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733682BDBM733682(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 2.68nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733699BDBM733699(2-((2-((4-(((3-(1-methylacryloyl piperidin-3-yl)ph...)
Affinity DataIC50: 2.93nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733689BDBM733689(2-(((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)a...)
Affinity DataIC50: 3.41nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733702BDBM733702((E)-2-((2-((4-(((3-(1-(but-2-enoyl)piperidin-3-yl)...)
Affinity DataIC50: 3.43nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733683BDBM733683(N-((1-acryloylpiperidin-4-yl)methyl)-4-((4-(2-(dim...)
Affinity DataIC50: 3.58nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733686BDBM733686(2-((2-((4-(((4-(1-acryloylpyrrolidin-2-yl)phenyl)a...)
Affinity DataIC50: 3.71nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733700BDBM733700(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 3.75nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733701BDBM733701(N-methyl-2-((2-((4-(((3-(1-propionylpiperidin-3-yl...)
Affinity DataIC50: 3.93nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733698BDBM733698(7-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 4.33nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733691BDBM733691(N-(3-(((2-((4-(((3-(N-acryloylpiperidin-3-yl)pheny...)
Affinity DataIC50: 4.36nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733697BDBM733697(7-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 4.98nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733703BDBM733703(2-((2-((4-(((3-(1-(2-fluoroacryloyl)piperidin-3-yl...)
Affinity DataIC50: 5.11nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733688BDBM733688(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 5.67nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733685BDBM733685((N-(1-acryloylpiperidin-4-yl)methyl)-4-((4-((2-(di...)
Affinity DataIC50: 5.79nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733694BDBM733694(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 6.13nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733693BDBM733693(2-((2-((4-(((3(1-acryloylpiperidin-3-yl)phenyl)ami...)
Affinity DataIC50: 6.73nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733692BDBM733692(2-(2-(4-((3-(1-aryloylpiperidin-3-yl)phenylamino)m...)
Affinity DataIC50: 7.84nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733696BDBM733696(2-((2-((4-(((3-(1-acryloylpiperidine-3-yl)phenyl)a...)
Affinity DataIC50: 10.4nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733687BDBM733687(1-(3-(3-((4-((4-((2-(dimethylphosphoryl)phenyl)ami...)
Affinity DataIC50: 15.8nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733695BDBM733695(2-((2-((4-(((3-(1-acryloylpiperidin-1-yl)phenyl)am...)
Affinity DataIC50: 17.9nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Signet Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 733690BDBM733690(2-((2-((4-(((3-(1-acryloylpiperidin-3-yl)phenyl)am...)
Affinity DataIC50: 19.8nMAssay Description:SupplierReagent HEPES Life TechnologiesBRIJ 35 detergent (10%) MerckMgCl2 SigmaHTRF KinEASE-TK kit CisbioFAK SignalchemATP PromegaDTT (DL-Dithiothrei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent