Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 12858
TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734323BDBM734323(US20250129032, Example 31)
Affinity DataIC50: 1.06nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734315BDBM734315((S)-5-(1-fluoro-3-hydroxy-7-((methylamino)methyl)-...)
Affinity DataIC50: 2nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734322BDBM734322(US20250129032, Example 30)
Affinity DataIC50: 2.28nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734302BDBM734302(US20250129032, Example 10)
Affinity DataIC50: 5nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734293BDBM734293((R)-5-(7-(2-aminoethyl)-1-fluoro-3-hydroxy-6,7,8,9...)
Affinity DataIC50: 5.07nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734298BDBM734298(US20250129032, Example 6)
Affinity DataIC50: 5.67nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734308BDBM734308(US20250129032, Example 16)
Affinity DataIC50: 10.7nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734311BDBM734311(US20250129032, Example 19)
Affinity DataIC50: 12.4nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734312BDBM734312(US20250129032, Example 20)
Affinity DataIC50: 12.7nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734306BDBM734306(US20250129032, Example 14)
Affinity DataIC50: 13.6nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734296BDBM734296(US20250129032, Example 4)
Affinity DataIC50: 14.9nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734295BDBM734295(US20250129032, Example 3)
Affinity DataIC50: 16.5nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734297BDBM734297(US20250129032, Example 5)
Affinity DataIC50: 17.5nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734318BDBM734318(US20250129032, Example 26)
Affinity DataIC50: 19.8nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734304BDBM734304(US20250129032, Example 12)
Affinity DataIC50: 19.8nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734325BDBM734325(US20250129032, Example 33)
Affinity DataIC50: 21.1nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734301BDBM734301(US20250129032, Example 9)
Affinity DataIC50: 21.6nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734314BDBM734314(US20250129032, Example 22)
Affinity DataIC50: 24.5nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734317BDBM734317(5-(1-fluoro-3-hydroxy-8-(isopentylamino)-6,7,8,9-t...)
Affinity DataIC50: 25.9nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734320BDBM734320(US20250129032, Example 28)
Affinity DataIC50: 39.9nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734324BDBM734324(US20250129032, Example 32)
Affinity DataIC50: 46.9nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734300BDBM734300(US20250129032, Example 8)
Affinity DataIC50: 47.3nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734316BDBM734316(US20250129032, Example 24)
Affinity DataIC50: 75nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734307BDBM734307(US20250129032, Example 15)
Affinity DataIC50: 79.5nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734305BDBM734305(US20250129032, Example 13)
Affinity DataIC50: 85.3nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734309BDBM734309(US20250129032, Example 17)
Affinity DataIC50: 93nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734321BDBM734321(US20250129032, Example 29)
Affinity DataIC50: 109nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734303BDBM734303(US20250129032, Example 11)
Affinity DataIC50: 149nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734294BDBM734294(US20250129032, Example 2)
Affinity DataIC50: 176nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734319BDBM734319(US20250129032, Example 27)
Affinity DataIC50: 215nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734313BDBM734313(US20250129032, Example 21)
Affinity DataIC50: 374nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734299BDBM734299(US20250129032, Example 7)
Affinity DataIC50: 444nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 734310BDBM734310(US20250129032, Example 18)
Affinity DataIC50: 879nMAssay Description:Compound activity was determined in an in vitro enzymatic assay using untagged, full-length human PTPN2 (TC45) (1-387) protein. PTPN2 was produced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent