Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 12860
TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734349BDBM734349(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.230nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734353BDBM734353(2-(5-methoxy-2-methylphenyl)-1-[(3S)- | US20250129...)
Affinity DataKi:  0.230nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734366BDBM734366(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.25nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734381BDBM734381((2R)-2-(3,5-dimethoxyphenyl)-1-[(3S)- | US20250129...)
Affinity DataKi:  0.280nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734383BDBM734383(1-[(3S)-3-({5-[5-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.290nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734380BDBM734380(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734341BDBM734341(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734339BDBM734339(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734343BDBM734343(2-fluoro-1-[(3S)-3-{[6-methyl-5-(1- | US2025012904...)
Affinity DataKi:  0.340nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734345BDBM734345(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.450nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734350BDBM734350((2R)-1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US2025...)
Affinity DataKi:  0.460nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734338BDBM734338(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.460nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734355BDBM734355(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.480nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734362BDBM734362(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.490nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734360BDBM734360(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.490nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734351BDBM734351((2R)-2-(5-chloro-2-methoxypyridin-4- | US202501290...)
Affinity DataKi:  0.510nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734378BDBM734378(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.530nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734389BDBM734389(2-[3-(difluoromethoxy)-5- | US20250129048, Example...)
Affinity DataKi:  0.770nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50617052BDBM50617052(CHEMBL5411999 | US20250129048, Example 7)
Affinity DataKi:  0.770nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734347BDBM734347(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.830nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734329BDBM734329((2R)-2-(5-Chloro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  0.880nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734374BDBM734374(2-(3,4-dichlorophenyl)-1-[(3S)-3-({5-[2- | US20250...)
Affinity DataKi:  0.880nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734387BDBM734387((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)- | US20250...)
Affinity DataKi:  0.910nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734369BDBM734369(2-[2-(difluoromethoxy)-6- | US20250129048, Example...)
Affinity DataKi:  0.930nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734375BDBM734375((2,2-difluoro-1-phenylcyclopropyl)[(3S)- | US20250...)
Affinity DataKi:  0.950nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734333BDBM734333((2R)-1-[(3S)-3-({5-[5-(1,1-Difluoroethyl)-1-methyl...)
Affinity DataKi:  1nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734370BDBM734370(2-(3-methoxy-4-methylphenyl)-1-[(3S)- | US20250129...)
Affinity DataKi:  1nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734358BDBM734358(2-(4-chlorophenyl)-1-[(3S)-3-({5-[2- | US202501290...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734373BDBM734373(1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734340BDBM734340((2R)-1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US2025...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734335BDBM734335((2R)-2-(5-Chloro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50617053BDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734337BDBM734337((2R)-1-[(3S)-3-({5-[1-Cyclopropyl-5-(difluoromethy...)
Affinity DataKi:  1.20nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734386BDBM734386((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)- | US20250...)
Affinity DataKi:  1.30nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734385BDBM734385(1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  2nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734364BDBM734364(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  2.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734357BDBM734357(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  2.10nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734334BDBM734334((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  2.60nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734332BDBM734332(1-[(3R)-2,2-Dimethyl-3-{[6-methyl-5-(1-methyl-1H-i...)
Affinity DataKi:  4.20nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734376BDBM734376(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  4.30nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734371BDBM734371(1-[(3S)-3-{[5-(1,5-dimethyl-1H-pyrazol- | US202501...)
Affinity DataKi:  5.5nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734367BDBM734367(1-[(3S)-3-{[5-(6,6-difluoro-6,7-dihydro- | US20250...)
Affinity DataKi:  6.90nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734342BDBM734342(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  7.70nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734359BDBM734359(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  20nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734382BDBM734382(1-[(3S)-3-({5-[5-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  54nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734379BDBM734379(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  62nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734361BDBM734361(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  88nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734356BDBM734356(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  120nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734346BDBM734346(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  150nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 734377BDBM734377(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  150nMAssay Description:The binding affinity of test compounds at the α-melanocyte-stimulating hormone receptor (hMC4R) was assessed using a radioligand competition binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

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