Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 12861
TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734391BDBM734391(US20250129049, Example 3)
Affinity DataIC50: 0.160nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734408BDBM734408(US20250129049, Example 20)
Affinity DataIC50: 0.200nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734394BDBM734394(US20250129049, Example 6)
Affinity DataIC50: 0.210nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734415BDBM734415(US20250129049, Example 27)
Affinity DataIC50: 0.220nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734393BDBM734393(US20250129049, Example 5)
Affinity DataIC50: 0.230nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734403BDBM734403(US20250129049, Example 15)
Affinity DataIC50: 0.230nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734390BDBM734390(US20250129049, Example 2)
Affinity DataIC50: 0.25nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734407BDBM734407(US20250129049, Example 19)
Affinity DataIC50: 0.260nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734392BDBM734392(US20250129049, Example 4)
Affinity DataIC50: 0.270nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734405BDBM734405(US20250129049, Example 17)
Affinity DataIC50: 0.270nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734402BDBM734402(US20250129049, Example 14)
Affinity DataIC50: 0.270nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734411BDBM734411(US20250129049, Example 23)
Affinity DataIC50: 0.300nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734412BDBM734412(US20250129049, Example 24)
Affinity DataIC50: 0.310nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734419BDBM734419(US20250129049, Example 31)
Affinity DataIC50: 0.310nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734420BDBM734420(US20250129049, Example 32)
Affinity DataIC50: 0.330nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734417BDBM734417(US20250129049, Example 29)
Affinity DataIC50: 0.330nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734406BDBM734406(US20250129049, Example 18)
Affinity DataIC50: 0.340nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734398BDBM734398(US20250129049, Example 10)
Affinity DataIC50: 0.340nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734414BDBM734414(US20250129049, Example 26)
Affinity DataIC50: 0.340nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734409BDBM734409(US20250129049, Example 21)
Affinity DataIC50: 0.370nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734336BDBM734336(5-({5-[7-(3-aminopropoxy)quinolin-8-yl]-1H-pyrazol...)
Affinity DataIC50: 0.370nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734400BDBM734400(US20250129049, Example 12)
Affinity DataIC50: 0.380nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734410BDBM734410(US20250129049, Example 22)
Affinity DataIC50: 0.390nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734399BDBM734399(US20250129049, Example 11)
Affinity DataIC50: 0.390nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734401BDBM734401(US20250129049, Example 13)
Affinity DataIC50: 0.420nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734418BDBM734418(US20250129049, Example 30)
Affinity DataIC50: 0.430nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734416BDBM734416(US20250129049, Example 28)
Affinity DataIC50: 0.430nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734413BDBM734413(US20250129049, Example 25)
Affinity DataIC50: 0.430nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734404BDBM734404(US20250129049, Example 16)
Affinity DataIC50: 0.450nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734424BDBM734424(US20250129049, Example 36)
Affinity DataIC50: 0.460nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734425BDBM734425(US20250129049, Example 37)
Affinity DataIC50: 0.490nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734396BDBM734396(US20250129049, Example 8)
Affinity DataIC50: 0.5nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50524300BDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 0.540nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734423BDBM734423(US20250129049, Example 35)
Affinity DataIC50: 0.600nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734397BDBM734397(US20250129049, Example 9)
Affinity DataIC50: 0.640nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734422BDBM734422(US20250129049, Example 34)
Affinity DataIC50: 0.75nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734426BDBM734426(US20250129049, Example 38)
Affinity DataIC50: 0.930nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734395BDBM734395(US20250129049, Example 7)
Affinity DataIC50: 1.71nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 734421BDBM734421(US20250129049, Example 33)
Affinity DataIC50: 9.28nMAssay Description:IMAP TR-FRET Screening Express Kit (R8160) was obtained from Molecular Devices. CHK1 kinase (02-117, Carna Bio), FAM-labeled CHKltide (R7185, Molecul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent