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Found
24
Enz. Inhib. hit(s) with all data for entry = 12885
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737441
(US20250136608, Compound 6-2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM50391992
(INCB018424 SALT | Jakafi | RUXOLITINIB PHOSPHATE |...)
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Copy InChI
Affinity Data
IC50: 1.30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737437
(US20250136608, Compound 3)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737436
(US20250136608, Compound 2-2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737434
(US20250136608, Compound 1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737435
(US20250136608, Compound 2-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737442
(US20250136608, Compound 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737439
(US20250136608, Compound 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.60nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737440
(US20250136608, Compound 6-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737438
(US20250136608, Compound 4)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11.1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737444
(US20250136608, Compound 9)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13.3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK2
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737443
(US20250136608, Compound 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM50391992
(INCB018424 SALT | Jakafi | RUXOLITINIB PHOSPHATE |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37.8nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737436
(US20250136608, Compound 2-2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 61.4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737441
(US20250136608, Compound 6-2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 116nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737435
(US20250136608, Compound 2-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 122nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737437
(US20250136608, Compound 3)
Copy SMILES
Copy InChI
Affinity Data
IC50: 151nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737434
(US20250136608, Compound 1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 241nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737440
(US20250136608, Compound 6-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 311nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737444
(US20250136608, Compound 9)
Copy SMILES
Copy InChI
Affinity Data
IC50: 401nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737438
(US20250136608, Compound 4)
Copy SMILES
Copy InChI
Affinity Data
IC50: 402nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737443
(US20250136608, Compound 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 419nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737442
(US20250136608, Compound 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 479nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Tyrosine-protein kinase JAK3
(Human)
Cgenetech (Suzhou, China) Co.
US Patent
Ligand
BDBM737439
(US20250136608, Compound 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 488nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL