Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 12888
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737516BDBM737516(Synthesis of 1-((3R,5R,8S,10S,13S,14S,17S)-3-hydro...)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737515BDBM737515(US20250136638, Example 9)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737514BDBM737514(US20250136638, Example 8)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737508BDBM737508(Synthesis of 1-(2-((3R,5S,8S,10S,13S,14S,17S)-3-hy...)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737523BDBM737523(US20250136638, Example 17)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737519BDBM737519(US20250136638, Example 13)
Affinity DataIC50: 55nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737517BDBM737517(US20250136638, Example 11)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737513BDBM737513(US20250136638, Example 7)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737512BDBM737512(Synthesis of 1-((3R,5S,8S,10S,13S,14S,17S)-3-hydro...)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737511BDBM737511(US20250136638, Example 5)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737510BDBM737510(Synthesis of 1-((3R,5S,8S,10S,13S,14S,17S)-3-hydro...)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737507BDBM737507(US20250136638, Example 1)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737522BDBM737522(US20250136638, Example 16)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737521BDBM737521(US20250136638, Example 15)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737518BDBM737518(Synthesis 1-((3R,5R,8S,10S,13S,14S,17S)-3-hydroxy-...)
Affinity DataIC50: 550nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737509BDBM737509(Synthesis of 1-(2-((3R,5S,8S,10S,13S,14S,17S)-3-hy...)
Affinity DataIC50: 5.50E+3nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 737520BDBM737520(US20250136638, Example 14)
Affinity DataIC50: 5.50E+3nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent