Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12899
TargetKetohexokinase(Human)TBA
LigandPNGBDBM738719(2-((1R,5S,6R)-3-(5-cyano-6-((S)- 2-methylazetidine...)
Affinity DataIC50: 0.170nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738731(Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-m...)
Affinity DataIC50: 0.390nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738730(Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-m...)
Affinity DataIC50: 0.440nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738157(US20250145619, Example 38)
Affinity DataIC50: 7.29nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738740(2-(1-(7,7-difluoro-2-((S)-2- methylazetidine-1-yl)...)
Affinity DataIC50: 10.4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM319585(US10174007, Example 4 | US10787438, Example 4 | US...)
Affinity DataIC50: 10.5nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738722(3-(1-(5-cyano-6-((S)-2-methylazetidine- 1-yl)-4-(t...)
Affinity DataIC50: 12.6nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738721((R)-2-((1R,5S,6R)-3-(5-cyano-6- ((S)-2-methylazeti...)
Affinity DataIC50: 12.6nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 13.6nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738728(Preparation of 3-((S)-1-(5-cyano-6-((S)-2-methylaz...)
Affinity DataIC50: 15.4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738747(US20250145619, Example 40)
Affinity DataIC50: 17.3nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM50629380(CHEMBL5430902 | US20250145619, Example 6)
Affinity DataIC50: 19.1nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738727(Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)...)
Affinity DataIC50: 24.7nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738720((S)-2-(2-(5-cyano-6-(2-methylazetidine- 1-yl)-4-(t...)
Affinity DataIC50: 27nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738712(US20250145619, Example 1)
Affinity DataIC50: 27.9nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738749(US20250145619, Example 46)
Affinity DataIC50: 30.2nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738745(US20250145619, Example 37)
Affinity DataIC50: 33.3nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738718(2-(5-cyano-6-((S)-2-methylazetidine- 1-yl)-4-(trif...)
Affinity DataIC50: 36nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738742((S)-2-(2-(7,7-difluoro-2-(2- methylazetidine-1-yl)...)
Affinity DataIC50: 40nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738734((S)-6-(7,7-difluoro-2-(2-methylazetidine- 1-yl)-6,...)
Affinity DataIC50: 42.9nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738733((S)-2-(1-(7,7-difluoro-2-(2-methylazetidine- 1-yl)...)
Affinity DataIC50: 47nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738741((S)-2-(1-(7,7-difluoro-2-(2- methylazetidine-1-yl)...)
Affinity DataIC50: 52.8nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738735(2-(7,7-difluoro-2-((S)-2-methylazetidine- 1-yl)-6,...)
Affinity DataIC50: 59nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738732(US20250145619, Example 24)
Affinity DataIC50: 78.3nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738729(Preparation of 3-((S)-1-(5-cyano-6-((S)-2-methylaz...)
Affinity DataIC50: 81.2nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738726(Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)...)
Affinity DataIC50: 100nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738716(US20250145619, Example 5)
Affinity DataIC50: 110nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738714((S)-7-(5-cyano-6-(2- methylazetidine-1-yl)-4- (tri...)
Affinity DataIC50: 115nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738739(2-(7,7-difluoro-2-((2S,3R)-3-hydroxy- 2-methylazet...)
Affinity DataIC50: 134nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738743(2-(5-(7,7-difluoro-2-((S)-2- methylazetidine-1-yl)...)
Affinity DataIC50: 142nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738713((S)-2-(5-cyano-6-(2- methylazetidine-1-yl)-4- (tri...)
Affinity DataIC50: 143nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738715((S)-6-(2,2-dioxa-2-thioxa-6- azaspiro[3.3]heptan-6...)
Affinity DataIC50: 198nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738723(US20250145619, Example 15)
Affinity DataIC50: 212nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738748(2-((R)-1-(5-((S)-2-methylazetidine- 1-yl)pyridino[...)
Affinity DataIC50: 3.94E+3nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738724(US20250145619, Example 16)
Affinity DataIC50: 6.31E+3nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738725(US20250145619, Example 17)
Affinity DataIC50: 1.00E+4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738738(2-(7,7-difluoro-2-((2S,3R)-3- methoxy-2-methylazet...)
Affinity DataIC50: 1.00E+4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738737(2-(7,7-difluoro-2-((2S,3R)-2- methyl-3-(methylamin...)
Affinity DataIC50: 1.00E+4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetKetohexokinase(Human)TBA
LigandPNGBDBM738736(2-(2-((2S,3R)-3-acetamido-2- methylazetidine-1-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent