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Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 12905
TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662989BDBM662989(Synthesis of N-(5-((1H-pyrazol-1-yl)methyl)-3,4-di...)
Affinity DataIC50: 0.300nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739500BDBM739500(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.300nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739493BDBM739493(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.400nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662990BDBM662990(Synthesis of N-(5-((1H-pyrazol-1-yl)methyl)-3,4-di...)
Affinity DataIC50: 0.5nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739494BDBM739494(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.5nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662985BDBM662985(Synthesis of 7-chloro-1-(2-chlorophenyl)-4-(prop-2...)
Affinity DataIC50: 0.600nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662989BDBM662989(Synthesis of N-(5-((1H-pyrazol-1-yl)methyl)-3,4-di...)
Affinity DataIC50: 0.700nMAssay Description:a. 1× buffer 2: 50 mM Tris-HCl, pH 7.8; 0.1 mM EDTA; 0.01% v/v tween-20; 1 mM DTT; 0.01% m/v bovine serum albumin.b. KAT6B enzyme solution: 3 nM (fin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739496BDBM739496(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.700nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739495BDBM739495(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.700nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739497BDBM739497(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 0.900nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739492BDBM739492(N-(4-((1H-pyrazol-1-yl)methyl)-2,2-difluoro-[1,3]d...)
Affinity DataIC50: 1nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662985BDBM662985(Synthesis of 7-chloro-1-(2-chlorophenyl)-4-(prop-2...)
Affinity DataIC50: 1.10nMAssay Description:a. 1× buffer 2: 50 mM Tris-HCl, pH 7.8; 0.1 mM EDTA; 0.01% v/v tween-20; 1 mM DTT; 0.01% m/v bovine serum albumin.b. KAT6B enzyme solution: 3 nM (fin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 722767BDBM722767(US20250059204, Compound 44 | US20250145637, Exampl...)
Affinity DataIC50: 1.20nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 662990BDBM662990(Synthesis of N-(5-((1H-pyrazol-1-yl)methyl)-3,4-di...)
Affinity DataIC50: 1.40nMAssay Description:a. 1× buffer 2: 50 mM Tris-HCl, pH 7.8; 0.1 mM EDTA; 0.01% v/v tween-20; 1 mM DTT; 0.01% m/v bovine serum albumin.b. KAT6B enzyme solution: 3 nM (fin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739492BDBM739492(N-(4-((1H-pyrazol-1-yl)methyl)-2,2-difluoro-[1,3]d...)
Affinity DataIC50: 1.5nMAssay Description:a. 1× buffer 2: 50 mM Tris-HCl, pH 7.8; 0.1 mM EDTA; 0.01% v/v tween-20; 1 mM DTT; 0.01% m/v bovine serum albumin.b. KAT6B enzyme solution: 3 nM (fin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739498BDBM739498(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 1.60nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739502BDBM739502(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 1.90nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 722787BDBM722787(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 2.70nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 722778BDBM722778(US20250059204, Compound 55 | US20250145637, Exampl...)
Affinity DataIC50: 2.90nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739491BDBM739491(N-(5-((1H-pyrazol-1-yl)methyl)-2,3-dihydro-[1,4]di...)
Affinity DataIC50: 4.20nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739507BDBM739507(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 4.60nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739508BDBM739508(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 4.70nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739509BDBM739509(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 4.80nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739511BDBM739511((R)-2,6-dimethoxy-N-(4-(tetrahydrofuran-2-yl)-2,3-...)
Affinity DataIC50: 5.20nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739503BDBM739503(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 10.5nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739510BDBM739510(2,6-dimethoxy-N-(4-(tetrahydrofuran-2-yl)-2,3-dihy...)
Affinity DataIC50: 12.2nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739504BDBM739504(N-(4-((1H-pyrazol-1-yl)methyl)-2,3-dihydrobenzofur...)
Affinity DataIC50: 12.5nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 739499BDBM739499(N-(5-((1H-pyrazol-1-yl)methyl)-3,4-dihydro-2H-chro...)
Affinity DataIC50: 12.5nMAssay Description:a. The prepared enzyme solution was added to a 384-well plate at 3 μL/well, and 3 μL of 1× assay buffer was added to each well in columns 23 and 24 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent