Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 12930
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 5.20nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741288(N-(8-amino-7-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 50nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741287(N-(8-amino-7-fluoro-6-(1-isopropyl-1H- pyrrole-2-y...)
Affinity DataIC50: 50nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741282(N-(8-amino-6-(1-ethyl-1H-pyrrole-2-yl)-7- fluorois...)
Affinity DataIC50: 50nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741281(N-(8-amino-7-fluoro-6-(1-ethenyl-1H- pyrrole-2-yl)...)
Affinity DataIC50: 50nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741280(N-(8-amino-7-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 50nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741283(N-(8-amino-7-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 100nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741286(N-(8-amino-7-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 200nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741289(N-(7-cyano-8-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 300nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741285(N-(8-amino-6-(1-ethyl-1H-pyrrole-2-yl)-7- fluorois...)
Affinity DataIC50: 300nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Asclepieion Pharmaceutical

US Patent
LigandPNGBDBM741284(N-(8-amino-7-fluoro-6-(1-methyl-1H- pyrrole-2-yl)i...)
Affinity DataIC50: 300nMAssay Description:The compound dilution was transferred into 384-well plate by using a pipette, afterwards, the 384-well plate was sealed and centrifuged at 1000 g for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent