Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 12941
TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743224BDBM743224(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  13nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743236BDBM743236(Preparation of (S)—N-1-(4-bromophenyl)ethyl-2-(6-m...)
Affinity DataEC50:  15nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743221BDBM743221(Preparation of (S)—N-(1-(4-fluorophenyl)ethyl-2-(6...)
Affinity DataEC50:  19nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743230BDBM743230(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  19nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743222BDBM743222(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  21nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743243BDBM743243(Preparation of (S)-2 (6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  22nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743233BDBM743233(Preparation of (S)—N-(1-(naphthalen-1-ethyl)-2-(4-...)
Affinity DataEC50:  23nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743226BDBM743226(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(6-...)
Affinity DataEC50:  23nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743223BDBM743223(Preparation of (S)—N-(1-(4-methoxyphenyl)ethyl-2-(...)
Affinity DataEC50:  24nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743218BDBM743218(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  25nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743241BDBM743241(Preparation of (S)—N-(1-(4-fluorophenyl)-2-methylp...)
Affinity DataEC50:  26nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743215BDBM743215(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  28nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743219BDBM743219(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(4-...)
Affinity DataEC50:  30nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743234BDBM743234(Preparation of (S)—N-(1-(4-bromophenyl)ethyl-2-(4-...)
Affinity DataEC50:  33nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743229BDBM743229(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  34nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743235BDBM743235(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  42nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743220BDBM743220(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  45nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743232BDBM743232(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(6,...)
Affinity DataEC50:  56nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743214BDBM743214(Preparation of (S)—N-(1-(4-fluorophenyl)ethyl-2-(4...)
Affinity DataEC50:  56nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743238BDBM743238(Preparation of (S)—N-(2-methyl-1-phenylpropyl)-2-(...)
Affinity DataEC50:  57nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743216BDBM743216(Preparation of (S)—N-(1-(4-methoxyphenyl)ethyl)-2-...)
Affinity DataEC50:  60nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743237BDBM743237(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  61nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 263368BDBM263368((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...)
Affinity DataEC50:  61nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743240BDBM743240(Preparation of (S)—N-(2-methyl-1-(4-trifluoromethy...)
Affinity DataEC50:  61nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743244BDBM743244(US20250163065, Compound I-46)
Affinity DataEC50:  68nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743225BDBM743225(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  75nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743228BDBM743228(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  93nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743227BDBM743227(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  95nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743231BDBM743231(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  96nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743217BDBM743217(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  111nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743239BDBM743239(Preparation of (S)—N-(1-(4-fluorophenyl)-2-methylp...)
Affinity DataEC50:  120nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetProbable G-protein coupled receptor 139(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 743242BDBM743242(Preparation of (S)—N-(2-methyl-1-(4-trifluoromethy...)
Affinity DataEC50:  125nMAssay Description:Determination of the Agonistic Activity of the Compounds of the Present Disclosure on GPR139More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent