Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 12944
TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600614(US11629146, Compound 1 | US20250163068, Compound 1)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600613(US11629146, Compound 98 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600612(US11629146, Compound 62 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743438(US20250163068, Compound 41)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743437(US20250163068, Compound 122)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743436(US20250163068, Compound 97)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600619(US11629146, Compound 79 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600618(US11629146, Compound 116 | US20250163068, Compound...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600617(US11629146, Compound 70 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600616(US11629146, Compound 48 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600615(US11629146, Compound 76 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743441(US20250163068, Compound 47)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600624(US11629146, Compound 56 | US20250163068, Compound ...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600623(US11629146, Compound 118 | US20250163068, Compound...)
Affinity DataIC50: 10nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600684(US11629146, Compound 136 | US20250163068, Compound...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743446(US20250163068, Compound 113)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM50173494(CHEMBL3810347 | US11629146, Compound 108 | US20250...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600673(US11629146, Compound 52 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743443(US20250163068, Compound 46)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743442(US20250163068, Compound 112)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743454(US20250163068, Compound 84)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600682(US11629146, Compound 77 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600681(US11629146, Compound 66 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600680(US11629146, Compound 12 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600679(US11629146, Compound 3 | US20250163068, Compound 3)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600678(US11629146, Compound 6 | US20250163068, Compound 6)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600677(US11629146, Compound 72 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600676(US11629146, Compound 73 | US20250163068, Compound ...)
Affinity DataIC50: 20nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600689(US11629146, Compound 30 | US20250163068, Compound ...)
Affinity DataIC50: 65nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743459(US20250163068, Compound 105)
Affinity DataIC50: 65nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600687(US11629146, Compound 63 | US20250163068, Compound ...)
Affinity DataIC50: 65nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600686(US11629146, Compound 49 | US20250163068, Compound ...)
Affinity DataIC50: 65nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600685(US11629146, Compound 117 | US20250163068, Compound...)
Affinity DataIC50: 65nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600691(US11629146, Compound 126 | US20250163068, Compound...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600691(US11629146, Compound 126 | US20250163068, Compound...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743468(US20250163068, Compound 107)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743467(US20250163068, Compound 42)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600695(US11629146, Compound 78 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600694(US11629146, Compound 96 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600693(US11629146, Compound 124 | US20250163068, Compound...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600692(US11629146, Compound 125 | US20250163068, Compound...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600703(US11629146, Compound 68 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600702(US11629146, Compound 59 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM743472(US20250163068, Compound 43)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)TBA
LigandPNGBDBM600700(US11629146, Compound 65 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent