Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 12979
TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747282BDBM747282(29 N,N-Dimethyl-2-(4-(2-(6- methylpyridin-2-yl)-6,...)
Affinity DataIC50: 0.180nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747320BDBM747320(71 (2-(4-(2-(6-Methylpyridin-2-yl)-5,6- dihydro-4H...)
Affinity DataIC50: 0.670nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747314BDBM747314(65 (3-Hydroxycyclobutyl)(2-(4-(2-(6- methylpyridin...)
Affinity DataIC50: 0.700nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747311BDBM747311(US20250179094, Compound 62 | US20250215017, Compou...)
Affinity DataIC50: 0.900nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747277BDBM747277(23 (2-(4-(1-Benzyl-3-(6-methylpyridin- 2-yl)-1H-py...)
Affinity DataIC50: 0.900nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747268BDBM747268(US20250179094, Compound 7)
Affinity DataIC50: 1.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747318BDBM747318(69 5-(Isopropylsulfonyl)-2-(4-(2-(6- methylpyridin...)
Affinity DataIC50: 1.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747303BDBM747303(54 2-[4-(3-(6-Methylpyridin-2-yl)-1- (pyridin-3-yl...)
Affinity DataIC50: 1.40nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747297BDBM747297(48 2-[4-(1-Benzyl-3-(6-methylpyridin-2- yl)-1H-pyr...)
Affinity DataIC50: 1.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747312BDBM747312(US20250179094, Compound 63 | US20250215017, Compou...)
Affinity DataIC50: 1.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747290BDBM747290(40 (2-(4-(1-(3-Fluorobenzyl)-3-(6- methylpyridin-2...)
Affinity DataIC50: 1.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747285BDBM747285(33 (2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-5H...)
Affinity DataIC50: 1.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747295BDBM747295(46 2-[4-(1-Isopropyl-3-(6-methylpyridin- 2-yl)-1H-...)
Affinity DataIC50: 1.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747323BDBM747323(74 N-Ethyl-N-methyl-2-(4-(2-(6- methylpyridin-2-yl...)
Affinity DataIC50: 1.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747309BDBM747309(60 2-(4-(1-Ethyl-3-(6-methylpyridin-2- yl)-1H-pyra...)
Affinity DataIC50: 1.80nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747307BDBM747307(58 N,N-Dimethyl-2-(4-(1-methyl-3-(6- methylpyridin...)
Affinity DataIC50: 1.80nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747286BDBM747286(34 (R)-(3-(Dimethylamino)pyrrolidin-1- yl)(2-(4-(2...)
Affinity DataIC50: 1.90nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747289BDBM747289(39 2-[4-(1-Methyl-3-(6-methylpyridin-2- yl)-1H-pyr...)
Affinity DataIC50: 2nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747321BDBM747321(72 (2-(4-(2-(6-Methylpyridin-2-yl)-5,6- dihydro-4H...)
Affinity DataIC50: 2nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747316BDBM747316(67 N,N-Dimethyl-2-(4-(2-(6- methylpyridin-2-yl)-5,...)
Affinity DataIC50: 2nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747301BDBM747301(52 5-(Ethylsulfonyl)-2-[4-(1-methyl-3-(6- methylpy...)
Affinity DataIC50: 2.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747270BDBM747270(10 (3-Hydroxycyclobutyl)(2-(4-(2-(6- methylpyridin...)
Affinity DataIC50: 2.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747299BDBM747299(50 2-[4-(1-(4-Fluorobenzyl)-3-(6- methylpyridin-2-...)
Affinity DataIC50: 2.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747319BDBM747319(70 (4-Hydroxypiperidin-1-yl)(2-(4-(2-(6- methylpyr...)
Affinity DataIC50: 2.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747284BDBM747284(32 N-Ethyl-N-methyl-2-(4-(2-(6- methylpyridin-2-yl...)
Affinity DataIC50: 2.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747302BDBM747302(53 2-[4-(3-(6-Methylpyridin-2-yl)-1- (pyridin-2-yl...)
Affinity DataIC50: 2.5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747292BDBM747292(43 (2-(4-(1-Cyclopropylmethyl-3-(6- methylpyridin-...)
Affinity DataIC50: 2.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747322BDBM747322(73 (1-Methylpiperidin-4-yl)(2-(4-(2-(6- methylpyri...)
Affinity DataIC50: 2.80nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747298BDBM747298(49 3-((3-(6-Methylpyridin-2-yl)-4-(2-(5- (methylsu...)
Affinity DataIC50: 3nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747296BDBM747296(47 2-[4-(1-(Cyclopropylmethyl)-3-(6- methylpyridin...)
Affinity DataIC50: 3.40nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747266BDBM747266(US20250179094, Compound 4)
Affinity DataIC50: 3.80nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747315BDBM747315(66 2-(4-(2-(6-Methylpyridin-2-yl)-5,6- dihydro-4H-...)
Affinity DataIC50: 4nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747279BDBM747279(26 3-((2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro...)
Affinity DataIC50: 4.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747272BDBM747272(12 1-(2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-...)
Affinity DataIC50: 4.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747280BDBM747280(27 (4-Hydroxypiperidin-1-yl)(2-(4-(2-(6- methylpyr...)
Affinity DataIC50: 4.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747288BDBM747288(38 (2-(4-(1-Ethyl-3-(6-methylpyridin-2- yl)-1H-pyr...)
Affinity DataIC50: 4.40nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747304BDBM747304(55 2-[4-(3-(6-Methylpyridin-2-yl)-1- (pyridin-4-yl...)
Affinity DataIC50: 5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747269BDBM747269(9 2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-5H-p...)
Affinity DataIC50: 5.40nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747300BDBM747300(51 2-[4-(1-(2-Fluorobenzyl)-3-(6- methylpyridin-2-...)
Affinity DataIC50: 5.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747324BDBM747324(75 2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-5H-...)
Affinity DataIC50: 5.60nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747283BDBM747283(30 Methyl 2-(4-(2-(6-Methylpyridin-2-yl)- 6,7-dihy...)
Affinity DataIC50: 5.70nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747293BDBM747293(44 3-(3-(6-Methylpyridin-2-yl)-4-(2- (1,4,5,6-tetr...)
Affinity DataIC50: 6.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747287BDBM747287(37 (2-(4-(1-Methyl-3-(6-methylpyridin-2- yl)-1H-py...)
Affinity DataIC50: 6.5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747310BDBM747310(US20250179094, Compound 61 | US20250215017, Compou...)
Affinity DataIC50: 6.90nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747313BDBM747313(64 3-(2-(4-(2-(6-Methylpyridin-2-yl)-6,7- dihydro-...)
Affinity DataIC50: 7.30nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747265BDBM747265(US20250179094, Compound 3 | US20250215017, Compoun...)
Affinity DataIC50: 7.40nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747276BDBM747276(22 (2-(4-(1-Isopropyl-3-(6- methylpyridin-2-yl)-1H...)
Affinity DataIC50: 7.5nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747274BDBM747274(14 (2-(4-(2-(6-Methylpyridin-2-yl)- 6,7-dihydro-5H...)
Affinity DataIC50: 7.90nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747317BDBM747317(68 5-(Ethylsulfonyl)-2-(4-(2-(6- methylpyridin-2-y...)
Affinity DataIC50: 8.10nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 747308BDBM747308(59 N,N-Dimethyl-2-(4-(3-(6- methylpyridin-2-yl)-1H...)
Affinity DataIC50: 9.20nMAssay Description:The principle of the activity assay was that TGFβR1 phosphorylates the substrate TGFβR1tide, consuming ATP in the process. This experiment employed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

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