Compile Data Set for Download or QSAR
Report error Found 102 Enz. Inhib. hit(s) with all data for entry = 12995
TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748816BDBM748816((S)-3-amino-N-(piperidin-3-yl)-6-(4- (1-(2,2,2-tri...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748784BDBM748784((S)-3-amino-6-(2-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748821BDBM748821(3-amino-6-(5-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo ...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748783BDBM748783(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748820BDBM748820((S)-3-amino-6-(5-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748782BDBM748782((S)-3-amino-6-(2-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748819BDBM748819(US20250188059, Example 42)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748780BDBM748780(3-amino-6-(5-fluoro-2-(1-(2,2,2- trifluoroethyl)-1...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748818BDBM748818(3-amino-6-(3-(1-methyl-1H-pyrazol- 4-yl)phenyl)-N-...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748817BDBM748817(3-amino-6-(2-fluoro-5-(1-methyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748807BDBM748807((S)-3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748806BDBM748806(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(3-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748805BDBM748805(3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748811BDBM748811(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748800BDBM748800(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-h...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748840BDBM748840((S)-3-amino-6-(2-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748798BDBM748798((S)-3-amino-N-(piperidin-3-yl)-6-(2- (1-(2,2,2-tri...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748838BDBM748838(3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748837BDBM748837(3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748835BDBM748835(3-amino-N-(4,4-difluoropiperidin-3-y)-6- (3-(5,5-d...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748801BDBM748801((S)-3-amino-6-(2-hydroxy-5-(1-(2,2,2- trifluoroeth...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748841BDBM748841(3-amino-6-(2-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748826BDBM748826((S)-3-amino-6-(2-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748825BDBM748825(3-amino-6-(2-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748822BDBM748822(3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748833BDBM748833((S)-3-amino-6-(5-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748794BDBM748794(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(3-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748832BDBM748832(3-amino-6-(5-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748831BDBM748831(3-amino-6-(2-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748793BDBM748793((S)-3-amino-6-(3-(1-methyl-1H- pyrazol-4-yl)phenyl...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748792BDBM748792(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748828BDBM748828((S)-3-amino-6-(3-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748827BDBM748827((S)-3-amino-6-(2-(5,5-dimethyl-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 10nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748778BDBM748778(Preparation of(S)-4-azaspiro[2.5]octan-6-amine | U...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748817BDBM748817(3-amino-6-(2-fluoro-5-(1-methyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748814BDBM748814(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(5-(...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748781BDBM748781((S)-3-amino-N-(5,5-difluoropiperidin- 3-yl)-6-(5-f...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748819BDBM748819(US20250188059, Example 42)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748779BDBM748779(3-amino-6-(5-fluoro-2-(1-(2,2,2- trifluoroethyl)-1...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748818BDBM748818(3-amino-6-(3-(1-methyl-1H-pyrazol- 4-yl)phenyl)-N-...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748808BDBM748808((S)-3-amino-6-(5-(1-cyclopropyl-1H- pyrazol-4-yl)-...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748807BDBM748807((S)-3-amino-6-(3-(1-(2-hydroxy-2- methylpropyl)-1H...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748806BDBM748806(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(3-(...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748812BDBM748812(3-amino-6-(2-fluoro-5-(1-(2-hydroxy- 2-methylpropy...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748811BDBM748811(3-amino-N-((3S,5S)-5- fluoropiperidin-3-yl)-6-(2-(...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748839BDBM748839(3-amino-6-(3-(5,5-dimethyl-5,6-dihydro- 4H-pyrrolo...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748798BDBM748798((S)-3-amino-N-(piperidin-3-yl)-6-(2- (1-(2,2,2-tri...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748797BDBM748797((S)-3-amino-6-(2-(1-cyclopropyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748797BDBM748797((S)-3-amino-6-(2-(1-cyclopropyl-1H- pyrazol-4-yl)p...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Arum Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 748836BDBM748836((S)-3-amino-N-(5,5-difluoropiperidin-3- yl)-6-(3-(...)
Affinity DataIC50: 55nMAssay Description:The compounds of Examples 1 to 66 were diluted at various concentrations and transferred to a 384-well plate by 5 μl, and 10 μl of a mixed solution (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

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