Compile Data Set for Download or QSAR
Report error Found 248 Enz. Inhib. hit(s) with all data for entry = 13012
TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751423BDBM751423(8-(4-(2-((1R,4R)- 2,5- diazabicyclo [2.2.1]heptan-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751421BDBM751421(8-(4-(2-((1S,4S)- 2,5- diazabicyclo [2.2.1]heptan-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751420BDBM751420((R)-(4-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751228BDBM751228(2-(2-Chloro-4-(2-(4-methylpiperazin-1-yl)ethoxy)ph...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751356BDBM751356(8-(2-chloro-4-(2- (piperazin-1- yl)ethoxy)phenyl)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751419BDBM751419(8-(4-(2-(4,7- diazaspiro [2.5]octan-7- yl)ethoxy)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751418BDBM751418(1-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)- 9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751354BDBM751354((R)-8-(2-chloro- 4-(2-(piperazin-1- yl)ethoxy)phen...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751417BDBM751417(6-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)- 9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751416BDBM751416(1-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)- 9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751238BDBM751238(9-Benzyl-8-(2-chloro-4-((1-methylpiperidin-4-yl)me...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751302BDBM751302(1-(4-(2-(3-(9- benzyl-6-(1- methylcyclo- propoxy)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751236BDBM751236(3-(4-(1-Benzyl-5-isopropoxy-1H-benzo[d]imidazol-2-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751299BDBM751299(1-(4-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751362BDBM751362(9-(3- chlorobenzyl)-8- (4-methyl-6-(2- (piperazin-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751424BDBM751424((1S,4S)-2-(2-(4- (9-benzyl-6-(1- methylcyclo- prop...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751342BDBM751342(9-benzyl-8-(2- fluoro-4-(2-(4- methylpiperazin- 1-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751339BDBM751339(1-(3-(4-(9- benzyl-6-(1- methyl- cyclopropoxy)- 9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751274BDBM751274(9-benzyl-8-(2- chloro-4-((1- methylazepan-4- yl)ox...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751272BDBM751272(9-benzyl-8-(2- chloro-3-(2-(4- methyl- piperazin-1...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751223BDBM751223(2-(2-chloro-4-(2-(piperazin-1-yl)ethoxy)phenyl)-1-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751414BDBM751414(1-(2-(4-(9- benzyl-6-(1- methylcyclo- propoxy)-9H-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751413BDBM751413((R)-9-benzyl-8- (2-chloro-4-(2- (2- methylpiperazi...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751349BDBM751349(9-benzyl-8-(2- bromo-4-(2-(4- methylpiperazin-1- y...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751412BDBM751412((S)-9-benzyl-8- (2-chloro-4-(2- (2- methylpiperazi...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751347BDBM751347(9-benzyl-8-(2,6- dimethyl-4-(2- (4- methylpiperazi...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751409BDBM751409(8-(2-chloro-4-(2- (piperazin-1- yl)ethoxy) phenyl)...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751345BDBM751345((R)-4-(2-(4-(9- benzyl-6-(1- methyl- cyclopropoxy)...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751280BDBM751280(9-benzyl-8-(2- chloro-4-(2-(1- methyl- pyrrolidin-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751325BDBM751325(1-(4-(2-((5-(9- benzyl-6-(1- methylcyclopropoxy)- ...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751324BDBM751324(1-(4-(3-((5-(9- benzyl-6-(1- methylcyclopropoxy)- ...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751256BDBM751256(9-benzyl-6- isopropoxy- 8-(2- methyl-4- (2- (piper...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751270BDBM751270(9-benzyl-8-(2- chloro-3-(2- (piperazin-1- yl)ethox...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751269BDBM751269(1-(4-((4- (9-benzyl-6-(1- methylcyclo- propoxy)-9H...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751265BDBM751265(9-benzyl-8-(2-chloro-3- methoxyphenyl)-6-(1- methy...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751437BDBM751437(8-(2-chloro-4-(2- (piperazin-1- yl)ethoxy)phenyl)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751245BDBM751245(1-benzyl-2-(2- chloro-4-((1- methylazepan-4- yl)ox...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751436BDBM751436(8-(2-chloro-4-(2- (piperazin-1- yl)ethoxy)phenyl)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751244BDBM751244(1-benzyl-2-(2- chloro-4-((1- methylazepan-4- yl)ox...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751382BDBM751382(2-((8-(2-chloro-4- (2-(piperazin-1- yl)ethoxy)phen...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751253BDBM751253(1-benzyl-2-(2- chloro-4-(2-(1- methylpyrrolidin-2-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751252BDBM751252(1-(3- chlorobenzyl)-5- isopropoxy-2-(4- methyl-6-(...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751248BDBM751248(N-(3-(4-(1-benzyl- 5-isopropoxy-1H- benzo[d]imidaz...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751376BDBM751376(8-(2-chloro-4-(2- (piperazin-1- yl)ethoxy)phenyl)-...)
Affinity DataIC50: 2nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751295BDBM751295(9-benzyl-8-(2- chloro-4- (piperidin-4- yloxy)pheny...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751294BDBM751294((R)-9- benzyl-8-(2- chloro-4- (piperidin-3- yloxy)...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751303BDBM751303(9-benzyl-8-(2- chloro-3-((1- methylpiperidin- 4-yl...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751301BDBM751301(N-(3-(4-(9- benzyl-6-(1- methylcyclo- propoxy)-9H-...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751427BDBM751427((S)-9-benzyl-8- (2-chloro-4-(2- (3- methylpiperazi...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 751426BDBM751426((S)-2-(4-(2-(4-(9- benzyl-6-(1- methylcyclo- propo...)
Affinity DataIC50: 2.51nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

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