Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 13039
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753729BDBM753729(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753726BDBM753726(4-(4-((1R,5S)-8,8-difluoro-3-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754000BDBM754000(US20250206759, Example 56)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754031BDBM754031(US20250206759, Example 87)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754014BDBM754014(US20250206759, Example 70)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754011BDBM754011(US20250206759, Example 67)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753979BDBM753979(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753973BDBM753973(4-(Aminomethyl)-1-(8-fluoro-7-(3-hydroxynaphthalen...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754022BDBM754022(US20250206759, Example 78)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754021BDBM754021(US20250206759, Example 77)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754020BDBM754020(US20250206759, Example 76)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753986BDBM753986((4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753984BDBM753984(3-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754015BDBM754015(US20250206759, Example 71)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753997BDBM753997(US20250206759, Example 53)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754028BDBM754028(US20250206759, Example 84)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754027BDBM754027(US20250206759, Example 83)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754026BDBM754026(US20250206759, Example 82)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753679BDBM753679(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-7-(4...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754002BDBM754002(US20250206759, Example 58)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754017BDBM754017(US20250206759, Example 73)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753620BDBM753620(5-Ethynyl-4-(8-fluoro-4-((1-(hydroxymethyl)-2-oxab...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753999BDBM753999(US20250206759, Example 55)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753983BDBM753983(3-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753998BDBM753998(US20250206759, Example 54)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754029BDBM754029(US20250206759, Example 85)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753981BDBM753981((1R,5S)-3-(8-fluoro-7-(3-hydroxynaphthalen-1-yl)-2...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753995BDBM753995(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753987BDBM753987(4-(8-Fluoro-4-(3-(hydroxymethyl)piperazin-1-yl)-2-...)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753985BDBM753985(8-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754030BDBM754030(US20250206759, Example 86)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754012BDBM754012(US20250206759, Example 68)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754006BDBM754006(US20250206759, Example 62)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754005BDBM754005(US20250206759, Example 61)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754004BDBM754004(US20250206759, Example 60)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754003BDBM754003(US20250206759, Example 59)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754001BDBM754001(US20250206759, Example 57)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754013BDBM754013(US20250206759, Example 69)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754010BDBM754010(US20250206759, Example 66)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754009BDBM754009(US20250206759, Example 65)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754008BDBM754008(US20250206759, Example 64)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 754007BDBM754007(US20250206759, Example 63)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753990BDBM753990(3-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753989BDBM753989(4-(4-(3-Amino-i-oxa-8-azaspiro[4.5]deca-8-yl)-8-fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753988BDBM753988(1-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753996BDBM753996((4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753994BDBM753994(4-(4-((1R,5S,8s)-8-(3,3-difluoroazetidin-1-yl)-3-a...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753993BDBM753993(4-(4-((1R,5S)-8,8-difluoro-3-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753992BDBM753992(4-(4-(3,3-difluorooctahydro-5H-pyrrolo[3,2-c]pyrid...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 753991BDBM753991(2-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

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