Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 13039
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753729(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753726(4-(4-((1R,5S)-8,8-difluoro-3-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754000(US20250206759, Example 56)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754031(US20250206759, Example 87)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754014(US20250206759, Example 70)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754011(US20250206759, Example 67)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753979(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753973(4-(Aminomethyl)-1-(8-fluoro-7-(3-hydroxynaphthalen...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754022(US20250206759, Example 78)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754021(US20250206759, Example 77)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754020(US20250206759, Example 76)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753986((4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753984(3-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754015(US20250206759, Example 71)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753997(US20250206759, Example 53)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754028(US20250206759, Example 84)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754027(US20250206759, Example 83)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754026(US20250206759, Example 82)
Affinity DataIC50: 100nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753679(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-7-(4...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754002(US20250206759, Example 58)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754017(US20250206759, Example 73)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753620(5-Ethynyl-4-(8-fluoro-4-((1-(hydroxymethyl)-2-oxab...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753999(US20250206759, Example 55)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753983(3-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753998(US20250206759, Example 54)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754029(US20250206759, Example 85)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753981((1R,5S)-3-(8-fluoro-7-(3-hydroxynaphthalen-1-yl)-2...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753995(4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8...)
Affinity DataIC50: 300nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753987(4-(8-Fluoro-4-(3-(hydroxymethyl)piperazin-1-yl)-2-...)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753985(8-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754030(US20250206759, Example 86)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754012(US20250206759, Example 68)
Affinity DataIC50: 750nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754006(US20250206759, Example 62)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754005(US20250206759, Example 61)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754004(US20250206759, Example 60)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754003(US20250206759, Example 59)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754001(US20250206759, Example 57)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754013(US20250206759, Example 69)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754010(US20250206759, Example 66)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754009(US20250206759, Example 65)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754008(US20250206759, Example 64)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM754007(US20250206759, Example 63)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753990(3-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753989(4-(4-(3-Amino-i-oxa-8-azaspiro[4.5]deca-8-yl)-8-fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753988(1-(8-Fluoro-7-(3-hydroxynaphthalen-1-yl)-2-((tetra...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
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TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753996((4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753994(4-(4-((1R,5S,8s)-8-(3,3-difluoroazetidin-1-yl)-3-a...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753993(4-(4-((1R,5S)-8,8-difluoro-3-azabicyclo[3.2.1]octa...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753992(4-(4-(3,3-difluorooctahydro-5H-pyrrolo[3,2-c]pyrid...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM753991(2-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octa-3-yl)-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 384-well reaction plate (Corning, CLS4514), 0.1 microliter of the compound was added. After centrifugation, a mixture of 5 microliters of Tag2-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent

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