Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 13164
TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764441(US20250255878, Compound TM1-11)
Affinity DataIC50: 0.690nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
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TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764448(3-((2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 1.34nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
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TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764438(2-((2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 1.47nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
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TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764437(US20250255878, Compound TM1-3)
Affinity DataIC50: 2.49nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
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TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764442(2-((2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 3.15nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764443(1-(2-((2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxypheny...)
Affinity DataIC50: 3.81nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764440(US20250255878, Compound TM1-10)
Affinity DataIC50: 4.03nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764447((2S,3R,4R,5S)-3-(3,4-difluoro-2-methoxyphenyl)-4,5...)
Affinity DataIC50: 4.27nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764439(2-((2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 4.29nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764446(6-(3-aminopropanamido)-4-((2R,3S,4S,5R)-3-(3,4-dif...)
Affinity DataIC50: 4.52nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
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TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764444(US20250255878, Compound TM1-27)
Affinity DataIC50: 6.11nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764444(US20250255878, Compound TM1-27)
Affinity DataIC50: 7.01nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM764445(4-carbamoyl-2-((2R,3S,4S,5R)-3-(3,4-difluoro-2-met...)
Affinity DataIC50: 10.1nMAssay Description:The Nav1.8 current is evoked by a 20 ms step voltage pulse to −10 mV from a holding potential of −80 mV at every 10 sec. The maximum amount of peak c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
Go to US Patent