Compile Data Set for Download or QSAR
Report error Found 232 Enz. Inhib. hit(s) with all data for entry = 13238
LigandChemical structure of BindingDB Monomer ID 50629518BDBM50629518(CHEMBL5412259 | US20250282782, Compound 222)
Affinity DataIC50: 1nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50629514BDBM50629514(CHEMBL5402623 | US20250282782, Compound 186)
Affinity DataIC50: 2nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50629515BDBM50629515(CHEMBL5402432 | US20250282782, Compound 192)
Affinity DataIC50: 2nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769580BDBM769580(US20250282782, Compound 3)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769684BDBM769684(US20250282782, Compound 42)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769843BDBM769843(US20250282782, Compound 201)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50629513BDBM50629513(CHEMBL5397998 | US20250282782, Compound 183)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769695BDBM769695(US20250282782, Compound 53)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769676BDBM769676(US20250282782, Compound 34)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50629516BDBM50629516(CHEMBL5411170 | US20250282782, Compound 193)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50629517BDBM50629517(CHEMBL5423545 | US20250282782, Compound 208)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769582BDBM769582(US20250282782, Compound 5)
Affinity DataIC50: 3nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769831BDBM769831(US20250282782, Compound 189)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769796BDBM769796(US20250282782, Compound 154)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769761BDBM769761(US20250282782, Compound 119)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769696BDBM769696(US20250282782, Compound 54)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769760BDBM769760(US20250282782, Compound 118)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769874BDBM769874((5S)-1'-[7-[(2-amino-3-chloro-4-pyridyl)sulfanyl]-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769723BDBM769723(US20250282782, Compound 81)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769817BDBM769817(US20250282782, Compound 175)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769719BDBM769719(US20250282782, Compound 77)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769781BDBM769781(US20250282782, Compound 139)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769685BDBM769685(US20250282782, Compound 43)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769780BDBM769780(US20250282782, Compound 138)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769776BDBM769776(US20250282782, Compound 134)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769837BDBM769837(US20250282782, Compound 195)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769804BDBM769804(US20250282782, Compound 162)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769768BDBM769768(US20250282782, Compound 126)
Affinity DataIC50: 4nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769861BDBM769861((6S)-1'-[7-(3-Chloro-2-methyl-4-pyridyl)-6-methyl-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769716BDBM769716(US20250282782, Compound 74)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769715BDBM769715(US20250282782, Compound 73)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769681BDBM769681(US20250282782, Compound 39)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769823BDBM769823(US20250282782, Compound 181)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769726BDBM769726(US20250282782, Compound 84)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769693BDBM769693(US20250282782, Compound 51)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769836BDBM769836(US20250282782, Compound 194)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769754BDBM769754(US20250282782, Compound 112)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769816BDBM769816(US20250282782, Compound 174)
Affinity DataIC50: 5nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769579BDBM769579(US20250282782, Compound 2)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769750BDBM769750(US20250282782, Compound 108)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769578BDBM769578(US20250282782, Compound 1)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769845BDBM769845(US20250282782, Compound 203)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769747BDBM769747(US20250282782, Compound 105)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769779BDBM769779(US20250282782, Compound 137)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769667BDBM769667(US20250282782, Compound 25)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769590BDBM769590(US20250282782, Compound 8)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769818BDBM769818(US20250282782, Compound 176)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769674BDBM769674(US20250282782, Compound 32)
Affinity DataIC50: 6nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769612BDBM769612(US20250282782, Compound 13)
Affinity DataIC50: 7nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 769702BDBM769702(US20250282782, Compound 60)
Affinity DataIC50: 7nMAssay Description:Inhibition of SHP2 phosphatase activity was evaluated using human recombinant 6His-Nterm (SEQ ID NO: 1) SHP2 full-length (Thr2-Arg593, R&D system), N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

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