Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 13242
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770175BDBM770175(US20250282798, Compound 23)
Affinity DataIC50: 0.0200nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770179BDBM770179(US20250282798, Compound 32)
Affinity DataIC50: 0.0400nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770173BDBM770173(US20250282798, Compound 21)
Affinity DataIC50: 0.0600nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770181BDBM770181(US20250282798, Compound 54-2)
Affinity DataIC50: 0.150nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770174BDBM770174(US20250282798, Compound 22)
Affinity DataIC50: 0.170nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770171BDBM770171(US20250282798, Compound 18)
Affinity DataIC50: 0.200nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770177BDBM770177(US20250282798, Compound 25)
Affinity DataIC50: 0.200nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770172BDBM770172(US20250282798, Compound 20)
Affinity DataIC50: 0.300nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770216BDBM770216(US20250282798, Compound 33)
Affinity DataIC50: 0.300nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770217BDBM770217(US20250282798, Compound 24)
Affinity DataIC50: 0.310nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770176BDBM770176(US20250282798, Compound 24-3)
Affinity DataIC50: 0.330nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770183BDBM770183(US20250282798, Compound 57)
Affinity DataIC50: 0.380nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770182BDBM770182(US20250282798, Compound 54)
Affinity DataIC50: 0.410nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770180BDBM770180(US20250282798, Compound 40)
Affinity DataIC50: 0.430nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770164BDBM770164(US20250282798, Compound 11)
Affinity DataIC50: 0.600nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770161BDBM770161(US20250282798, Compound 4)
Affinity DataIC50: 0.620nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770163BDBM770163(US20250282798, Compound 9)
Affinity DataIC50: 0.700nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770178BDBM770178(US20250282798, Compound 29)
Affinity DataIC50: 0.740nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770169BDBM770169(US20250282798, Compound 16)
Affinity DataIC50: 0.800nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770184BDBM770184(US20250282798, Compound 63)
Affinity DataIC50: 0.900nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770186BDBM770186(US20250282798, Compound 70)
Affinity DataIC50: 0.900nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770165BDBM770165(US20250282798, Compound 12)
Affinity DataIC50: 0.900nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770170BDBM770170(US20250282798, Compound 17)
Affinity DataIC50: 1.30nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770185BDBM770185(US20250282798, Compound 68)
Affinity DataIC50: 1.40nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770167BDBM770167(US20250282798, Compound 14)
Affinity DataIC50: 1.40nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770168BDBM770168(US20250282798, Compound 15)
Affinity DataIC50: 1.70nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770162BDBM770162(US20250282798, Compound 8)
Affinity DataIC50: 2nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770166BDBM770166(US20250282798, Compound 13)
Affinity DataIC50: 2.10nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770159BDBM770159(US20250282798, Compound 5)
Affinity DataIC50: 3nMAssay Description:Table 1: Method 1: The IC50 value was assayed by 33P isotope-labeled kinase activity assay to evaluate the inhibitory ability of a test compound on h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770160BDBM770160(US20250282798, Compound 6)
Affinity DataIC50: 8nMAssay Description:Table 1: Method 1: The IC50 value was assayed by 33P isotope-labeled kinase activity assay to evaluate the inhibitory ability of a test compound on h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770158BDBM770158(US20250282798, Compound 2)
Affinity DataIC50: 18nMAssay Description:Table 1: Method 1: The IC50 value was assayed by 33P isotope-labeled kinase activity assay to evaluate the inhibitory ability of a test compound on h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770163BDBM770163(US20250282798, Compound 9)
Affinity DataIC50: 115nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770164BDBM770164(US20250282798, Compound 11)
Affinity DataIC50: 121nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770162BDBM770162(US20250282798, Compound 8)
Affinity DataIC50: 154nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770165BDBM770165(US20250282798, Compound 12)
Affinity DataIC50: 173nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770172BDBM770172(US20250282798, Compound 20)
Affinity DataIC50: 198nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770167BDBM770167(US20250282798, Compound 14)
Affinity DataIC50: 252nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770166BDBM770166(US20250282798, Compound 13)
Affinity DataIC50: 255nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770169BDBM770169(US20250282798, Compound 16)
Affinity DataIC50: 277nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 770161BDBM770161(US20250282798, Compound 4)
Affinity DataIC50: 594nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent