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Compile Data Set for Download or QSAR
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Found
173
Enz. Inhib. hit(s) with all data for entry = 13320
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778630
(US20250313575, Ex-6.2)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778623
(US20250313575, Ex-5.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778510
(US20250313575, Ex-1.2)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778574
(2-((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-3,...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778509
(US20250313575, Ex-1.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778637
((1R,2R)- or (1S,2S)-2-((10aS,13aS)-3- cyclopropyl-...)
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Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778636
((1R,2R)- or (1S,2S)-2-((10aS,13aS)-3- cyclopropyl-...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778635
(((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-3,4,...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778634
(((10aS,13aS)-3-cyclobutyl-8- (trifluoromethyl)-3,4...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778633
(((10aR,12aR)-3-isopropyl-8- (trifluoromcthyl)-3,4,...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778632
(US20250313575, Ex-6.4)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778675
(US20250313575, Ex-19.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778609
((10aR,12aR)-3-(3-methoxycyclobutyl)-1- methyl-8-(t...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778544
((10aR,12aS)- or (10aS,12aR)-1,3-dimethyl-8- (trifl...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778608
((10aR,12aR)-8-chloro-3-(3- methoxycyclobutyl)-1-me...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778620
(US20250313575, Ex-3.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778554
((10aR,12aS)- or (10aS,12aR)-3-cyclobutyl-1-methyl-...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778661
(US20250313575, Ex-15.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778595
((10aR,12aR)-3-cyclobutyl-1-((R)- (10aR,12aR)-3-cyc...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778530
((10aR,12aR)-3-isopropyl-8- (trifluoromethyl)- 1,4,...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778594
((10aR,12aR)-3-cyclobutyl-1-((R)- (10aR,12aR)-3-cyc...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778529
(1-((10aR,12aR)-3-cyclopropyl-8- (trifluoromethyl)-...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778542
((10aR,12aS)- or (10aS,12aR)-1,3-dimethyl-8- (trifl...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778541
((10aR,12aR)- or (10aS,12aS)-1,3-dimethyl-8- (trifl...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778605
((10aR,12aR)-1-methyl-3-((S)- or (10aR,12aR)-1-meth...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778604
((10aR,12aR)-1-methyl-3-((S)- or (10aR,12aR)-1-meth...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778603
((10aR,12aR)- or (10aS,12aS)-3-cyclobutyl-1-(oxetan...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778536
(1',3'-dimethyl-10'-(trifluoromethyl)- 1',7',8',14'...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778600
((10aS,13aS)-3-cyclobutyl-1-((1S,2S)- or (10aS,13aS...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778599
((10aR,12aR)-3-cyclopropyl-1-methyl-8- (trifluorome...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778517
((10aR,12aS)- or (10aS,12aR)-3- cyclopropyl-1-methy...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778645
(US20250313575, Ex-10.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778580
((10aS,13aS)-8-chloro-3-cyclobutyl-1- methyl-3,4,10...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778515
((10aS,13aS)- or (10aR,13aR)-3- cyclopropyl-1-methy...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778579
(2-((10aS,13aS)-3-cyclobutyl-8- (trifluoromethyl)-3...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778643
(US20250313575, Ex-8.1)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778578
(ethyl (1R,2S)- or ethyl (1S,2R)-2-((10aS,13aS)-3-i...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778642
(2-((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-10...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778641
((R)-2-(3-isopropyl-11-methyl-8- (trifluoromethyl)-...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778640
((R)-2-(3,11-dimethyl-8-(trifluoromethyl)- 10,11,12...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778526
((10aR,12aR)-3-isopropyl-1-((R)- or (10aR,12aR)-3-i...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778654
((10aS,13aS)-3-isopropyl-1-methyl- 8-(trifluorometh...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778525
(2-((10aR,12aR)-3-cyclopropyl-8- (trifluoromethyl)-...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778652
((10aR,12aR)-8-chloro-3-cyclobutyl- 1-methyl-3,4,10...)
Copy SMILES
Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778587
((10aS,12aR)-8-chloro-3-cyclobutyl-1- methyl-3,4,10...)
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Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778650
(US20250313575, Ex-13.1)
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Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778648
(US20250313575, Ex-12.1)
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Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778519
((10aR,12aR)- or (10aS,12aS)-3- cyclopropyl-1-methy...)
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Affinity Data
IC50: 0.0810nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778627
((10aR,13aR)- or (10aS,13aS)-3-cyclobutyl-1-methyl-...)
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Affinity Data
IC50: 0.0870nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Human)
Merck Sharp & Dohme
US Patent
Ligand
BDBM778563
((10aS,13aS)- or (10aR,13aR)-3-((1R,3S)-3- methoxyc...)
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Affinity Data
IC50: 0.0910nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
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