Compile Data Set for Download or QSAR
Report error Found 340 Enz. Inhib. hit(s) with all data for entry = 13399
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786511BDBM786511(2,2-difluoro-3-({6- fluoro-4-[7- methoxy-6-(2- met...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786512BDBM786512((2R)-2-fluoro-3-({6- fluoro-4-[7- methoxy-6-(2- me...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786498BDBM786498(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786562BDBM786562(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786499BDBM786499(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- a]p...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786568BDBM786568(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786557BDBM786557(N-(5-(6- (cyclopropylsulfonyl)-7- methoxyimidazo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786558BDBM786558(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786481BDBM786481(1-(2-((4-(6-(tert- butylsulfonyl)-7- methoxyimidaz...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786293BDBM786293(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786423BDBM786423(N-(5-(5-(tert- butylsulfonyl)-6- methoxypyrazolo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786473BDBM786473(rac-4-((4-(6-(tert- butylsulfonyl)-7- methoxyimida...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786474BDBM786474((1s,3s)-3-((4-(6- (tert-butylsulfonyl)- 7- methoxy...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786475BDBM786475(rac-(1R,3S)-3-((4-(6- (tert-butylsulfonyl)- 7- met...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786476BDBM786476((1r,3r)-3-((4-(6- (tert-butylsulfonyl)- 7- methoxy...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786477BDBM786477(N1-(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786478BDBM786478((R)-3-((4-(6-(tert- butylsulfonyl)-7- methoxyimida...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786414BDBM786414(N-{3-methoxy-5-[7- methoxy-6-(2- methylpropane-2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786415BDBM786415(N-{3-[7-ethoxy-6- (propane-2- sulfonyl)imidazo[1,2...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786465BDBM786465(5-((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786529BDBM786529(Rac-1-({4-[7- ethoxy-6-(propane- 2- sulfonyl)imida...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786466BDBM786466(3-((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786467BDBM786467(5-(((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786468BDBM786468(5-(((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786469BDBM786469(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786470BDBM786470(1-(2-((4-(6-(tert- butylsulfonyl)-7- methoxyimidaz...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786471BDBM786471(4-(((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786472BDBM786472(4-((4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786600BDBM786600(US20250346593, Example 317)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786458BDBM786458(N-benzyl-4-(6-(tert- butylsulfonyl)-7- methoxyimid...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786522BDBM786522((4R or S)-4-[({6- fluoro-4-[7- methoxy-6-(2- methy...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786459BDBM786459(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786523BDBM786523((4R or S)-4-[2-({6- fluoro-4-[7- methoxy-6-(2- met...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786460BDBM786460(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786524BDBM786524((4R or S)-4-[2-({6- fluoro-4-[7- methoxy-6-(2- met...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786461BDBM786461(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786525BDBM786525(3-({4-[7-ethoxy-6- (4-fluoro-1- methylpiperidin-4-...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786462BDBM786462(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786526BDBM786526(3-({4-[7-ethoxy-6- (propane-2- sulfonyl)imidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786463BDBM786463(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786464BDBM786464(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786577BDBM786577(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786514BDBM786514((2S)-2-fluoro-3-({6- fluoro-4-[7- methoxy-6-(2- me...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786452BDBM786452(US20250346593, Example 169)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786516BDBM786516(4-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,2- ...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786453BDBM786453(US20250346593, Example 170)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786519BDBM786519((3S)-3-({6-fluoro-4- [7-methoxy-6-(2- methylpropan...)
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786563BDBM786563(N-(3-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Affinity DataIC50: 1.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786567BDBM786567(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Affinity DataIC50: 1.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Interline Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 786553BDBM786553(N-(5-(6-(tert- butylsulfonyl)-7- methoxyimidazo[1,...)
Affinity DataIC50: 1.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

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