Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 13485
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798329BDBM798329((R)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 7nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798190BDBM798190(N-(2-methyl-1H-pyrrolo[3,2-c]pyridin-6-yl)-5-(1H-p...)
Affinity DataIC50: 7nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798330BDBM798330((S)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 13nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798332BDBM798332((R)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 46nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798333BDBM798333((R)-N-(2-(1-methylpiperidin-2-yl)-1H-pyrrolo[3,2-c...)
Affinity DataIC50: 64nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798331BDBM798331((R)-2-fluoro-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyr...)
Affinity DataIC50: 67nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798336BDBM798336((R)-4-(5-fluoro-1H-pyrazol-4-yl)-N-(2-(1-methylpyr...)
Affinity DataIC50: 73nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798335BDBM798335((R)-4-(5-(methoxymethyl)-1H-pyrazol-4-yl)-N-(2-(1-...)
Affinity DataIC50: 179nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798329BDBM798329((R)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 195nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798332BDBM798332((R)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 274nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798334BDBM798334((R)-N-(2-(1-methylpiperidin-2-yl)-1H-pyrrolo[3,2-c...)
Affinity DataIC50: 390nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798330BDBM798330((S)-N-(2-(1-methylpyrrolidin-2-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 1.30E+4nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

TargetProtein ENL(Human)
Bridge Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 798190BDBM798190(N-(2-methyl-1H-pyrrolo[3,2-c]pyridin-6-yl)-5-(1H-p...)
Affinity DataIC50: 3.00E+4nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent