Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 13486
LigandChemical structure of BindingDB Monomer ID 798393BDBM798393(3-Amino-6-(1-bicyclo[1.1.1]pentanylmethoxy)-4-(7-f...)
Affinity DataIC50: 9.70nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50664869BDBM50664869(CHEMBL6162828 | US20260078122, Example 84)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798452BDBM798452(US20260078122, Example 123)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798451BDBM798451(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-8-methyl-7-(o...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798454BDBM798454(US20260078122, Example 125)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798520BDBM798520(US20260078122, Example 192)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798453BDBM798453(US20260078122, Example 124)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661049BDBM50661049(CHEMBL6147496 | US20260078122, Example 127)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798455BDBM798455(3-Amino-7-cyclopentyl-4-(7-fluoro-1H-indazol-4-yl)...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661047BDBM50661047(CHEMBL6143148 | US20260078122, Example 128)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798462BDBM798462(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-8-methyl-7-(2...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798461BDBM798461(US20260078122, Example 132)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50664870BDBM50664870(CHEMBL6174255 | US20260078122, Example 103)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798438BDBM798438(3-Amino-8-chloro-6-cyclopropyl-4-(7-fluoro-1H-inda...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50664872BDBM50664872(CHEMBL6162753 | US20260078122, Example 175)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661040BDBM50661040(CHEMBL6151763 | US20260078122, Example 77)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798440BDBM798440(US20260078122, Example 111)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798442BDBM798442(US20260078122, Example 113)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798441BDBM798441(US20260078122, Example 112)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798444BDBM798444(3-Amino-7-bromo-4-(7-fluoro-1H-indazol-4-yl)-8-met...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798512BDBM798512(US20260078122, Example 184)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798445BDBM798445(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-7-iodo-8-meth...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661038BDBM50661038(CHEMBL6165232 | US20260078122, Example 17)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798355BDBM798355(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-7-methyl-6-(4...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798359BDBM798359(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-7-methyl-6-(2...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798463BDBM798463(3-Amino-7-(1,1-difluoroethyl)-4-(7-fluoro-1H-indaz...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50664868BDBM50664868(CHEMBL6169181 | US20260078122, Example 3)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661033BDBM50661033(CHEMBL6145586 | US20260078122, Example 15)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798482BDBM798482(US20260078122, Example 154)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798382BDBM798382(3-Amino-7-chloro-4-(7-fluoro-1H-indazol-4-yl)-6-me...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661042BDBM50661042(CHEMBL6164722 | US20260078122, Example 156)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661032BDBM50661032(CHEMBL6143411 | US20260078122, Example 158)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798386BDBM798386(3-Amino-7-chloro-4-(7-fluoro-1H-indazol-4-yl)-6,8-...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798389BDBM798389(3-Amino-6-(2,2-difluoroethoxy)-4-(7-fluoro-1H-inda...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798388BDBM798388(1-[[7-Amino-8-(7-fluoro-1H-indazol-4-yl)-3-methyl-...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798487BDBM798487(3-Amino-4-(7-chloro-1H-indazol-4-yl)-6,7-dimethyl-...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798424BDBM798424(3-Amino-6-chloro-7-cyclopropyl-4-(7-fluoro-1H-inda...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50664871BDBM50664871(CHEMBL6151576 | US20260078122, Example 162)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798390BDBM798390(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-6-methoxy-7-m...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798492BDBM798492(3-Amino-5-chloro-4-(7-fluoro-1H-indazol-4-yl)-8-me...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798491BDBM798491(3-Amino-5-chloro-7-cyclopropyl-4-(7-fluoro-1H-inda...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798428BDBM798428(3-Amino-7-chloro-4-(7-fluoro-1H-indazol-4-yl)-8-me...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798394BDBM798394(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-6-isopropoxy-...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798493BDBM798493(3-amino-7-cyclopropyl-4-(7-fluoro-1H-indazol-4-yl)...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798430BDBM798430(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-8-methyl-7-(t...)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661048BDBM50661048(CHEMBL6143248 | US20260078122, Example 100)
Affinity DataIC50: 10nMAssay Description:The cellular potency of Compound 1 in suppressing intracellular 2-HG levels was determined in cell lines expressing five different mutated IDH-1 prot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661023BDBM50661023(CHEMBL6144020 | US20260078122, Example 37)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798375BDBM798375(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-7-methyl-6-pi...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798377BDBM798377(3-Amino-6-(cyclopropylmethoxy)-4-(7-fluoro-1H-inda...)
Affinity DataIC50: 10nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 798476BDBM798476(3-Amino-4-(7-fluoro-1H-indazol-4-yl)-6-(3-hydroxy-...)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

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