Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 10905
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277505BDBM277505(US20260098044, Example 22)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277505BDBM277505(US20260098044, Example 22)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277508BDBM277508(US20260098044, Example 23)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277508BDBM277508(US20260098044, Example 23)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277537BDBM277537(US20260098044, Example 26)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277537BDBM277537(US20260098044, Example 26)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277549BDBM277549(US20260098044, Example 27)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277549BDBM277549(US20260098044, Example 27)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277509BDBM277509(US20260098044, Example 24)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277509BDBM277509(US20260098044, Example 24)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277534BDBM277534(US20260098044, Example 25)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277534BDBM277534(US20260098044, Example 25)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277551BDBM277551(US20260098044, Example 28)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277551BDBM277551(US20260098044, Example 28)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277552BDBM277552(US20260098044, Example 29)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277552BDBM277552(US20260098044, Example 29)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39771BDBM39771(US20260098044, Example 1)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39771BDBM39771(US20260098044, Example 1)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39772BDBM39772(US20260098044, Example 2)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39772BDBM39772(US20260098044, Example 2)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39782BDBM39782(US20260098044, Example 8)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39782BDBM39782(US20260098044, Example 8)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39777BDBM39777(US20260098044, Example 5)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39777BDBM39777(US20260098044, Example 5)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39779BDBM39779(US20260098044, Example 6)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39779BDBM39779(US20260098044, Example 6)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39796BDBM39796(US20260098044, Example 11)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39796BDBM39796(US20260098044, Example 11)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39788BDBM39788(US20260098044, Example 9)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39788BDBM39788(US20260098044, Example 9)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277394BDBM277394(US20260098044, Example 15)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277394BDBM277394(US20260098044, Example 15)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39804BDBM39804(US20260098044, Example 14)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39804BDBM39804(US20260098044, Example 14)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277466BDBM277466(US20260098044, Example 19)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277466BDBM277466(US20260098044, Example 19)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277435BDBM277435(US20260098044, Example 17)
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39781BDBM39781(US20260098044, Example 7)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277408BDBM277408(US20260098044, Example 16)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277408BDBM277408(US20260098044, Example 16)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277486BDBM277486(US20260098044, Example 21)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277486BDBM277486(US20260098044, Example 21)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39776BDBM39776(US20260098044, Example 4)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277435BDBM277435(US20260098044, Example 17)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277460BDBM277460(US20260098044, Example 18)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277460BDBM277460(US20260098044, Example 18)
Affinity DataIC50: 75nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39781BDBM39781(US20260098044, Example 7)
Affinity DataIC50: 200nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 277470BDBM277470(US20260098044, Example 20)
Affinity DataIC50: 200nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39801BDBM39801(US20260098044, Example 13)
Affinity DataIC50: 200nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 39774BDBM39774(US20260098044, Example 3)
Affinity DataIC50: 200nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent

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