Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 9283
TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455543BDBM455543(US20260116867, Compound A3)
Affinity DataEC50:  3.20nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 65456BDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataEC50:  9nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455427BDBM455427(US20260116867, Compound A2)
Affinity DataEC50:  11nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455371BDBM455371(US20260116867, Compound A1)
Affinity DataEC50:  14nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455454BDBM455454(US20260116867, Compound M8)
Affinity DataEC50:  15nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455493BDBM455493(US20260116867, Compound M7)
Affinity DataEC50:  17nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455539BDBM455539(US20260116867, Compound M10)
Affinity DataEC50:  23nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455540BDBM455540(US20260116867, Compound M11)
Affinity DataEC50:  24nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455361BDBM455361(US20260116867, Compound M4)
Affinity DataEC50:  31nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 50070114BDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataEC50:  36nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455523BDBM455523(US20260116867, Compound M9)
Affinity DataEC50: >333nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455494BDBM455494(US20260116867, Compound M6)
Affinity DataEC50:  410nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 429515BDBM429515(US10550091, No. LC-1 | US10947203, No. LC-1 | US20...)
Affinity DataEC50: >3.00E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent