Compile Data Set for Download or QSAR
Report error Found 664 Enz. Inhib. hit(s) with all data for entry = 9953
TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803159BDBM803159(US20260116881, Compound 308)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803160BDBM803160(US20260116881, Compound 309)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803161BDBM803161(US20260116881, Compound 310)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803162BDBM803162(US20260116881, Compound 311)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803163BDBM803163(US20260116881, Compound 312)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803164BDBM803164(US20260116881, Compound 313)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803165BDBM803165(US20260116881, Compound 314)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803151BDBM803151(US20260116881, Compound 300)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803152BDBM803152(US20260116881, Compound 301)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803155BDBM803155(US20260116881, Compound 304)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803157BDBM803157(US20260116881, Compound 306)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803175BDBM803175(US20260116881, Compound 324)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803176BDBM803176(US20260116881, Compound 325)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803178BDBM803178(US20260116881, Compound 327)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803181BDBM803181(US20260116881, Compound 330)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803182BDBM803182(US20260116881, Compound 331)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803168BDBM803168(US20260116881, Compound 317)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803169BDBM803169(US20260116881, Compound 318)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803170BDBM803170(US20260116881, Compound 319)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803172BDBM803172(US20260116881, Compound 321)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803174BDBM803174(US20260116881, Compound 323)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803192BDBM803192(US20260116881, Compound 341)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803283BDBM803283(US20260116881, Compound 432)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803282BDBM803282(US20260116881, Compound 431)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803285BDBM803285(US20260116881, Compound 434)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803286BDBM803286(US20260116881, Compound 435)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803273BDBM803273(US20260116881, Compound 422)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803185BDBM803185(US20260116881, Compound 334)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803186BDBM803186(US20260116881, Compound 335)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803277BDBM803277(US20260116881, Compound 426)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803188BDBM803188(US20260116881, Compound 337)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803276BDBM803276(US20260116881, Compound 425)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803189BDBM803189(US20260116881, Compound 338)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803279BDBM803279(US20260116881, Compound 428)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803190BDBM803190(US20260116881, Compound 339)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803278BDBM803278(US20260116881, Compound 427)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803297BDBM803297(US20260116881, Compound 446)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803296BDBM803296(US20260116881, Compound 445)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803299BDBM803299(US20260116881, Compound 448)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803210BDBM803210(Step 1: 2-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol...)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803211BDBM803211(US20260116881, Compound 360)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803212BDBM803212(US20260116881, Compound 361)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803213BDBM803213(US20260116881, Compound 362)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803214BDBM803214(US20260116881, Compound 363)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803199BDBM803199(US20260116881, Compound 348)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803202BDBM803202(US20260116881, Compound 351)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803203BDBM803203(US20260116881, Compound 352)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803204BDBM803204(US20260116881, Compound 353)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803205BDBM803205(US20260116881, Compound 354)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803223BDBM803223(US20260116881, Compound 372)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

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