Compile Data Set for Download or QSAR
Report error Found 590 Enz. Inhib. hit(s) with all data for entry = 13566
TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805022BDBM805022(US20260125375, Example C14)
Affinity DataKi:  0.400nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805163BDBM805163(US20260125375, Example D30)
Affinity DataKi:  0.600nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805019BDBM805019(US20260125375, Example C11)
Affinity DataKi:  0.600nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805161BDBM805161(US20260125375, Example D28)
Affinity DataKi:  0.600nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805009BDBM805009(US20260125375, Example C1)
Affinity DataKi:  0.600nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805243BDBM805243(US20260125375, Example I3)
Affinity DataKi:  0.700nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805161BDBM805161(US20260125375, Example D28)
Affinity DataKi:  0.700nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805208BDBM805208(US20260125375, Example D76)
Affinity DataKi:  0.700nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805055BDBM805055((1S,2S)-2-({(1S)-1-[3-{3-[(R)-cyclobutyl(4-methyl-...)
Affinity DataKi:  0.700nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805155BDBM805155(US20260125375, Example D22)
Affinity DataKi:  0.800nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805243BDBM805243(US20260125375, Example I3)
Affinity DataKi:  0.800nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805209BDBM805209(US20260125375, Example D77)
Affinity DataKi:  0.800nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805225BDBM805225(US20260125375, Example D93)
Affinity DataKi:  0.800nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805241BDBM805241(N-{(1ξ)-1-[3-{3-[(R)-cyclobutyl(4-methyl-4H-1,2,4-...)
Affinity DataKi:  0.800nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805148BDBM805148(US20260125375, Example D15)
Affinity DataKi:  0.900nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805020BDBM805020(US20260125375, Example C12)
Affinity DataKi:  0.900nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805152BDBM805152((2S)-1-({(1S)-1-[3-{3-[(R)-cyclobutyl(4-methyl-4H-...)
Affinity DataKi:  1nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805160BDBM805160(US20260125375, Example D27)
Affinity DataKi:  1nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805151BDBM805151((2S)-1-({(1R)-1-[3-{3-[(R)-cyclobutyl(4-methyl-4H-...)
Affinity DataKi:  1nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805238BDBM805238(N-{(1ξ)-1-[5-cyclopropyl-3-(3-{3-[(4-methyl-4H-1,2...)
Affinity DataKi:  1nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805148BDBM805148(US20260125375, Example D15)
Affinity DataKi:  1nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805016BDBM805016(US20260125375, Example C8)
Affinity DataKi:  1.10nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805203BDBM805203(US20260125375, Example D71)
Affinity DataKi:  1.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805233BDBM805233(US20260125375, Example F1)
Affinity DataKi:  1.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805165BDBM805165(3-{3-[(R)-cyclobutyl(4-methyl-4H-1,2,4-triazol-3-y...)
Affinity DataKi:  1.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805020BDBM805020(US20260125375, Example C12)
Affinity DataKi:  1.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805168BDBM805168(US20260125375, Example D36)
Affinity DataKi:  1.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805150BDBM805150(US20260125375, Example D17)
Affinity DataKi:  1.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805236BDBM805236((2S)-1-({(1ξ)-1-[3-{3-[(R)-cyclobutyl(4-methyl-4H-...)
Affinity DataKi:  1.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805153BDBM805153(US20260125375, Example D20)
Affinity DataKi:  1.70nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805159BDBM805159(US20260125375, Example D26)
Affinity DataKi:  1.80nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805156BDBM805156(US20260125375, Example D23)
Affinity DataKi:  1.80nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805044BDBM805044(US20260125375, Example C36)
Affinity DataKi:  1.80nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805162BDBM805162(US20260125375, Example D29)
Affinity DataKi:  1.90nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805241BDBM805241(N-{(1ξ)-1-[3-{3-[(R)-cyclobutyl(4-methyl-4H-1,2,4-...)
Affinity DataKi:  1.90nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805057BDBM805057(US20260125375, Example C49)
Affinity DataKi:  2.10nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805126BDBM805126(US20260125375, Example C118)
Affinity DataKi:  2.10nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805026BDBM805026(US20260125375, Example C18)
Affinity DataKi:  2.20nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805157BDBM805157(US20260125375, Example D24)
Affinity DataKi:  2.20nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805052BDBM805052(US20260125375, Example C44)
Affinity DataKi:  2.20nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805153BDBM805153(US20260125375, Example D20)
Affinity DataKi:  2.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805022BDBM805022(US20260125375, Example C14)
Affinity DataKi:  2.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805021BDBM805021(US20260125375, Example C13)
Affinity DataKi:  2.30nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [46-435](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805225BDBM805225(US20260125375, Example D93)
Affinity DataKi:  2.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805085BDBM805085(US20260125375, Example C77)
Affinity DataKi:  2.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805028BDBM805028(US20260125375, Example C20)
Affinity DataKi:  2.40nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805050BDBM805050(US20260125375, Example C42)
Affinity DataKi:  2.5nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805056BDBM805056(US20260125375, Example C48)
Affinity DataKi:  2.5nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805109BDBM805109(US20260125375, Example C101)
Affinity DataKi:  2.5nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B [36-427](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 805149BDBM805149(US20260125375, Example D16)
Affinity DataKi:  2.5nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

Displayed 1 to 50 (of 590 total ) | Next | Last >>
Jump to: