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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 13568
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805318BDBM805318(US20260125380, Example AMG473)
Affinity DataIC50: 370nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805316BDBM805316((S)-4-amino-N-methyl-N- (6-(perfluoroethyl)-2,3- d...)
Affinity DataIC50: 1.36E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805315BDBM805315((S)-4-amino-N- methyl-N-(6- (pentafluoro-l6- sulfa...)
Affinity DataIC50: 1.51E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805313BDBM805313((S)-4-amino-N-(methyl- d3)-N-(6-(trifluorometh- yl...)
Affinity DataIC50: 2.30E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805314BDBM805314((S)-4-amino-N-methyl-N- (6-(trifluoromethyl)-2,3- ...)
Affinity DataIC50: 4.50E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805311BDBM805311((S)-4-amino-N-methyl-N- (6-(trifluoromethyl)-2,3- ...)
Affinity DataIC50: 5.29E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805317BDBM805317((S)-4-amino-7-fluoro-N- (methyl-d3)-N-(6-(tri- flu...)
Affinity DataIC50: 8.16E+3nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 805312BDBM805312((S)-4-amino-7-fluoro-N- methyl-N-(6-(trifluoro- me...)
Affinity DataIC50: 1.14E+4nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent