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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 5873
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98040BDBM98040(US8486953, 53)
Affinity DataIC50: 6nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98034BDBM98034(US8486953, 9)
Affinity DataIC50: 27nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98032BDBM98032(US8486953, 2)
Affinity DataIC50: 28nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98035BDBM98035(US8486953, 10)
Affinity DataIC50: 34nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98040BDBM98040(US8486953, 53)
Affinity DataIC50: 35nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98033BDBM98033(US8486953, 6)
Affinity DataIC50: 35nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98036BDBM98036(US8486953, 19)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98039BDBM98039(US8486953, 48)
Affinity DataIC50: 92nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98034BDBM98034(US8486953, 9)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98038BDBM98038(US8486953, 41)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98032BDBM98032(US8486953, 2)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98041BDBM98041(US8486953, 71)
Affinity DataIC50: 160nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98033BDBM98033(US8486953, 6)
Affinity DataIC50: 180nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98038BDBM98038(US8486953, 41)
Affinity DataIC50: 210nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98035BDBM98035(US8486953, 10)
Affinity DataIC50: 210nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98041BDBM98041(US8486953, 71)
Affinity DataIC50: 400nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98039BDBM98039(US8486953, 48)
Affinity DataIC50: 460nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98037BDBM98037(US8486953, 34)
Affinity DataIC50: 560nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98036BDBM98036(US8486953, 19)
Affinity DataIC50: 590nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98037BDBM98037(US8486953, 34)
Affinity DataIC50: 680nMpH: 7.4Assay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent