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Found 16 Enz. Inhib. hit(s) with all data for entry = 5985
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)
Affinity DataKi:  2.14nM IC50:  4.61nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340727(2,5,7-Triimethyl-phenylsulfonyl-pyrazolo[1,5-a]pyr...)
Affinity DataKi:  68.4nM IC50:  147nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340728(2-{[5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]...)
Affinity DataKi:  222nM IC50:  477nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340729(5,7-Dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrim...)
Affinity DataKi:  237nM IC50:  510nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417908(CHEMBL1668574 | US8552005, 1.1(7))
Affinity DataIC50: <10nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417906(CHEMBL1668571 | US8552005, 1.1(11))
Affinity DataIC50:  20nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417907(CHEMBL1668572 | US8552005, 1.1(9))
Affinity DataIC50:  25nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340726(5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...)
Affinity DataIC50:  30nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417912(CHEMBL1668580 | US8552005, 1.1(20))
Affinity DataIC50:  46nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340730(5,7-Dimethyl-2-(ethylthio)-3-phenylsulfonyl-pyrazo...)
Affinity DataIC50:  50nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM103508(US8552005, 1.1(15))
Affinity DataIC50:  80nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417908(CHEMBL1668574 | US8552005, 1.1(7))
Affinity DataIC50:  112nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417928(CHEMBL1668573 | US8552005, 1.1(16))
Affinity DataIC50:  230nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM103509(US8552005, 1.1(18))
Affinity DataIC50:  320nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417910(CHEMBL1668577 | US8552005, 1.1(17))
Affinity DataIC50:  440nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50340729(5,7-Dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrim...)
Affinity DataIC50: >1.00E+3nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent