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Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 5983
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM103495(US8552023, 7)
Affinity DataKi:  0.0410nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM103499(US8552023, 11)
Affinity DataKi:  0.0500nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM103494(US8552023, 6)
Affinity DataKi:  0.0650nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM103501(US8552023, 13)
Affinity DataKi:  0.130nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM103496(US8552023, 8)
Affinity DataKi:  0.430nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent