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Found 10 Enz. Inhib. hit(s) with all data for entry = 6027
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382912(CHEMBL2023209 | US8569299, 4)
Affinity DataIC50:  0.5nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104819(US8569299, 8)
Affinity DataIC50:  0.800nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382886(CHEMBL2024198 | US8569299, 23)
Affinity DataIC50:  0.900nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104816(US8569299, 2)
Affinity DataIC50:  5.90nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104818(US8569299, 7)
Affinity DataIC50:  6.30nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50383424(CHEMBL2031591 | US8569299, 6)
Affinity DataIC50:  8.10nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104817(US8569299, 3)
Affinity DataIC50:  9.80nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382921(CHEMBL2024196 | US8569299, 5)
Affinity DataIC50:  10.7nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM104815(US8569299, 1)
Affinity DataIC50:  13.9nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50383422(CHEMBL2031594 | US8569299, 74)
Affinity DataIC50:  18nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent