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Found 423 Enz. Inhib. hit(s) with all data for entry = 6049
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106438(US8586579, 27)
Affinity DataKi:  1.40nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106438(US8586579, 27)
Affinity DataKi:  1.40nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106429(US8586579, 18)
Affinity DataKi:  1.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106435(US8586579, 24)
Affinity DataKi:  1.70nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106426(US8586579, 15)
Affinity DataKi:  1.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106430(US8586579, 19)
Affinity DataKi:  1.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106433(US8586579, 22)
Affinity DataKi:  2.20nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106431(US8586579, 20)
Affinity DataKi:  2.5nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106429(US8586579, 18)
Affinity DataKi:  2.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106436(US8586579, 25)
Affinity DataKi:  2.70nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106434(US8586579, 23)
Affinity DataKi:  2.70nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106442(US8586579, 31)
Affinity DataKi:  2.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106441(US8586579, 30)
Affinity DataKi:  2.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106422(US8586579, 11)
Affinity DataKi:  2.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106431(US8586579, 20)
Affinity DataKi:  3nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106437(US8586579, 26)
Affinity DataKi:  3nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106434(US8586579, 23)
Affinity DataKi:  3nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106433(US8586579, 22)
Affinity DataKi:  3.20nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106426(US8586579, 15)
Affinity DataKi:  3.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106430(US8586579, 19)
Affinity DataKi:  3.5nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106435(US8586579, 24)
Affinity DataKi:  3.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106432(US8586579, 21)
Affinity DataKi:  3.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106473(US8586579, 62)
Affinity DataKi:  3.62nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106432(US8586579, 21)
Affinity DataKi:  3.70nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106439(US8586579, 28)
Affinity DataKi:  4nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106495(US8586579, 84)
Affinity DataKi:  4.01nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106441(US8586579, 30)
Affinity DataKi:  4.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106442(US8586579, 31)
Affinity DataKi:  4.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106437(US8586579, 26)
Affinity DataKi:  4.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106419(US8586579, 8)
Affinity DataKi:  4.40nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106424(US8586579, 13)
Affinity DataKi:  4.40nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106529(US8586579, 118)
Affinity DataKi:  4.51nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106468(US8586579, 57)
Affinity DataKi:  4.52nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106507(US8586579, 96)
Affinity DataKi:  4.64nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106510(US8586579, 99)
Affinity DataKi:  4.80nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106436(US8586579, 25)
Affinity DataKi:  4.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106462(US8586579, 51)
Affinity DataKi:  5.07nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106428(US8586579, 17)
Affinity DataKi:  5.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106440(US8586579, 29)
Affinity DataKi:  5.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106420(US8586579, 9)
Affinity DataKi:  5.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106418(US8586579, 7)
Affinity DataKi:  5.60nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106516(US8586579, 105)
Affinity DataKi:  5.67nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106444(US8586579, 33)
Affinity DataKi:  5.90nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106469(US8586579, 58)
Affinity DataKi:  5.92nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106439(US8586579, 28)
Affinity DataKi:  6nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106421(US8586579, 10)
Affinity DataKi:  6.10nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106466(US8586579, 55)
Affinity DataKi:  6.14nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106454(US8586579, 43)
Affinity DataKi:  6.30nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106464(US8586579, 53)
Affinity DataKi:  6.37nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM106413(US8586579, 2)
Affinity DataKi:  6.40nMAssay Description:The ability of the compounds to bind to the 5-HT2A, D3 and D2 receptors was determined using radioligand binding to cloned receptors selectively expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
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