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Found 166 Enz. Inhib. hit(s) with all data for entry = 6085
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107901(US8604218, 1.052)
Affinity DataIC50:  15.3nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107948(US8604218, 1.099)
Affinity DataIC50:  25.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107938(US8604218, 1.089)
Affinity DataIC50:  29.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108011(US8604218, 2.025)
Affinity DataIC50:  29.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107930(US8604218, 1.081)
Affinity DataIC50:  30.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107931(US8604218, 1.082)
Affinity DataIC50:  30.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107908(US8604218, 1.059)
Affinity DataIC50:  32nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107951(US8604218, 1.102)
Affinity DataIC50:  34.3nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107949(US8604218, 1.100)
Affinity DataIC50:  42.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107907(US8604218, 1.058)
Affinity DataIC50:  47.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107940(US8604218, 1.091)
Affinity DataIC50:  49.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107926(US8604218, 1.077)
Affinity DataIC50:  53.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107896(US8604218, 1.047)
Affinity DataIC50:  57nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107921(US8604218, 1.072)
Affinity DataIC50:  58.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107973(US8604218, 1.124)
Affinity DataIC50:  59.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107900(US8604218, 1.051)
Affinity DataIC50:  62.6nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107927(US8604218, 1.078)
Affinity DataIC50:  63.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107857(US8604218, 1.008)
Affinity DataIC50:  65.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107950(US8604218, 1.101)
Affinity DataIC50:  68.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107883(US8604218, 1.034)
Affinity DataIC50:  69.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107955(US8604218, 1.106)
Affinity DataIC50:  69.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107886(US8604218, 1.037)
Affinity DataIC50:  69.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107923(US8604218, 1.074)
Affinity DataIC50:  71.6nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107992(US8604218, 2.006)
Affinity DataIC50:  73.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107924(US8604218, 1.075)
Affinity DataIC50:  74.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107882(US8604218, 1.033)
Affinity DataIC50:  86.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108017(US8604218, 2.031)
Affinity DataIC50:  87.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107909(US8604218, 1.060)
Affinity DataIC50:  87.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107987(US8604218, 2.001)
Affinity DataIC50:  98.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107942(US8604218, 1.093)
Affinity DataIC50:  101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108025(US8604218, 2.039)
Affinity DataIC50:  101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107928(US8604218, 1.079)
Affinity DataIC50:  102nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107873(US8604218, 1.024)
Affinity DataIC50:  107nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107953(US8604218, 1.104)
Affinity DataIC50:  107nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107969(US8604218, 1.120)
Affinity DataIC50:  109nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107922(US8604218, 1.073)
Affinity DataIC50:  111nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107925(US8604218, 1.076)
Affinity DataIC50:  111nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108024(US8604218, 2.038)
Affinity DataIC50:  112nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108013(US8604218, 2.027)
Affinity DataIC50:  120nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107903(US8604218, 1.054)
Affinity DataIC50:  132nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107972(US8604218, 1.123)
Affinity DataIC50:  135nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107865(US8604218, 1.016)
Affinity DataIC50:  135nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107890(US8604218, 1.041)
Affinity DataIC50:  137nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107889(US8604218, 1.040)
Affinity DataIC50:  144nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107956(US8604218, 1.107)
Affinity DataIC50:  148nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107911(US8604218, 1.062)
Affinity DataIC50:  155nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107895(US8604218, 1.046)
Affinity DataIC50:  156nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108022(US8604218, 2.036)
Affinity DataIC50:  160nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107929(US8604218, 1.080)
Affinity DataIC50:  162nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107913(US8604218, 1.064)
Affinity DataIC50:  165nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
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