Compile Data Set for Download or QSAR
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Found 284 Enz. Inhib. hit(s) with all data for entry = 6144
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111676(US8618111, B-63)
Affinity DataIC50:  0.610nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111632(US8618111, B-19)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111645(US8618111, B-32)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111635(US8618111, B-22)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111674(US8618111, B-61)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111647(US8618111, B-34)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111695(US8618111, B-82)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111631(US8618111, B-18)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111679(US8618111, B-66)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111636(US8618111, B-23 | US8618111, B-47)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111672(US8618111, B-59)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111649(US8618111, B-36)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111673(US8618111, B-60)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111694(US8618111, B-81)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111636(US8618111, B-23 | US8618111, B-47)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111629(US8618111, B-16)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111624(US8618111, B-11)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111690(US8618111, B-77)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111699(US8618111, B-86)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111654(US8618111, B-41)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111643(US8618111, B-30)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111627(US8618111, B-14)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111688(US8618111, B-75)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111618(US8618111, B-5)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111677(US8618111, B-64)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111657(US8618111, B-44)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111658(US8618111, B-45)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111639(US8618111, B-26)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111622(US8618111, B-9)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111666(US8618111, B-53)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111673(US8618111, B-60)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111643(US8618111, B-30)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111667(US8618111, B-54)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111752(US8618111, H-25)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111661(US8618111, B-48)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111750(US8618111, H-23)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111647(US8618111, B-34)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111734(US8618111, H-6)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111709(US8618111, F-1)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111676(US8618111, B-63)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111711(US8618111, F-3)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111625(US8618111, B-12)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111659(US8618111, B-46)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111656(US8618111, B-43)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111633(US8618111, B-20)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111713(US8618111, F-5)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111692(US8618111, B-79)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111651(US8618111, B-38)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111626(US8618111, B-13)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111741(US8618111, H-14)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent
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