Compile Data Set for Download or QSAR
Report error Found 490 Enz. Inhib. hit(s) with all data for entry = 6151
TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112421BDBM112421(US8623889, 420)
Affinity DataKi:  0.0186nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112312BDBM112312(US8623889, 311)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112359BDBM112359(US8623889, 358)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112161BDBM112161(US8623889, 159)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112230BDBM112230(US8623889, 228)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112111BDBM112111(US8623889, 109)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112193BDBM112193(US8623889, 191)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112066BDBM112066(US8623889, 64)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112105BDBM112105(US8623889, 103)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112274BDBM112274(US8623889, 272)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112289BDBM112289(US8623889, 287)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112029BDBM112029(US8623889, 27)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112288BDBM112288(US8623889, 286)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112106BDBM112106(US8623889, 104)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112275BDBM112275(US8623889, 273)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112251BDBM112251(US8623889, 249)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112099BDBM112099(US8623889, 97)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112144BDBM112144(US8623889, 142)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112252BDBM112252(US8623889, 250)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112032BDBM112032(US8623889, 30)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112192BDBM112192(US8623889, 190)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112245BDBM112245(US8623889, 243)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112244BDBM112244(US8623889, 242)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112255BDBM112255(US8623889, 253)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112078BDBM112078(US8623889, 76)
Affinity DataKi:  0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112254BDBM112254(US8623889, 252)
Affinity DataKi:  0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112194BDBM112194(US8623889, 192)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112157BDBM112157(US8623889, 155)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112289BDBM112289(US8623889, 287)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112288BDBM112288(US8623889, 286)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112065BDBM112065(US8623889, 63)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112379BDBM112379(US8623889, 378)
Affinity DataKi:  0.0709nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112418BDBM112418(US8623889, 417)
Affinity DataKi:  0.0723nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112439BDBM112439(US8623889, 438)
Affinity DataKi:  0.0799nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112438BDBM112438(US8623889, 437)
Affinity DataKi:  0.0799nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112330BDBM112330(US8623889, 329)
Affinity DataKi:  0.0800nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112408BDBM112408(US8623889, 407)
Affinity DataKi:  0.0841nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112409BDBM112409(US8623889, 408)
Affinity DataKi:  0.0841nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112425BDBM112425(US8623889, 424)
Affinity DataKi:  0.0896nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112057BDBM112057(US8623889, 55)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112245BDBM112245(US8623889, 243)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112107BDBM112107(US8623889, 105)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112058BDBM112058(US8623889, 56)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112224BDBM112224(US8623889, 222)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112244BDBM112244(US8623889, 242)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112191BDBM112191(US8623889, 189)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112058BDBM112058(US8623889, 56)
Affinity DataKi:  0.100nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112286BDBM112286(US8623889, 285 | US8623889, 284)
Affinity DataKi:  0.100nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112314BDBM112314(US8623889, 313)
Affinity DataKi:  0.100nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 112057BDBM112057(US8623889, 55)
Affinity DataKi:  0.100nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

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