Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 6147
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111821BDBM111821(US8623906, XW2-038H | US9174969, JHE-02-023)
Affinity DataIC50: 700nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111823BDBM111823(BDBM111857 | US8623906, JHE-02-069 | US8623906, JH...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111823BDBM111823(BDBM111857 | US8623906, JHE-02-069 | US8623906, JH...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111822BDBM111822(US8623906, XW2-125B | US9174969, XW2-125B)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111824BDBM111824(US8623906, JHE-02-119 | US9174969, JHE-02-119)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111826BDBM111826(US8623906, JHE-01-129A)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111832BDBM111832(US8623906, JHE-01-129B | US9174969, JHE-01-129B)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111873BDBM111873(US8623906, JHE-02-020B | US9174969, JHE-02-020B)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111828BDBM111828(US8623906, JHE-02-065B | US9174969, JHE-02-065B)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111844BDBM111844(US8623906, XW2-057 | US9174969, XW2-057)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111829BDBM111829(US8623906, JHE-02-068B | US9174969, JHE-02-068B)
Affinity DataIC50: 4.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111854BDBM111854(US8623906, JHE-02-017C | US9174969, JHE-02-017C)
Affinity DataIC50: 4.40E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111845BDBM111845(US8623906, XW2-124B | US9174969, XW2-124B)
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111865BDBM111865(US8623906, JHE-02-019A | US9174969, JHE-02-019A)
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111851BDBM111851(US8623906, XW2-036 | US9174969, XW2-036)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111837BDBM111837(US8623906, JHE-01-137 | US9174969, JHE-01-137)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111867BDBM111867(US8623906, XW2-038F | US9174969, XW2-038F)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111863BDBM111863(US8623906, JHE-02-017A | US9174969, JHE-02-017A)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111860BDBM111860(US8623906, JHE-01-155B | US9174969, JHE-01-155B)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111858BDBM111858(US8623906, JHE-02-010B | US9174969, JHE-02-010B)
Affinity DataIC50: 5.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111878BDBM111878(US8623906, JHE-02-019B | US9174969, JHE-02-019B)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111831BDBM111831(US8623906, JHE-02-068A | US9174969, JHE-02-068A)
Affinity DataIC50: 5.70E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111836BDBM111836(US8623906, JF020 | US9174969, JF020)
Affinity DataIC50: 5.70E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111850BDBM111850(US8623906, JHE-02-012 | US9174969, JHE-02-012)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111830BDBM111830(US8623906, XW2-038A | US8623906, XW3-002 | US91749...)
Affinity DataIC50: 6.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111833BDBM111833(US8623906, JF028 | US9174969, JF028)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111847BDBM111847(US8623906, JHE-02-017B | US9174969, JHE-02-017B)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111835BDBM111835(US8623906, JF026 | US9174969, JF026)
Affinity DataIC50: 6.90E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111870BDBM111870(US8623906, JHE-02-014 | US9174969, JHE-02-014)
Affinity DataIC50: 6.90E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111855BDBM111855(US8623906, JF023 | US9174969, JF023)
Affinity DataIC50: 7.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111843BDBM111843(US8623906, JF024 | US9174969, JF024)
Affinity DataIC50: 7.60E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111864BDBM111864(US8623906, JHE-02-010C | US9174969, JHE-02-010C)
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111862BDBM111862(US8623906, JHE-02-033A | US9174969, JHE-02-033A)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111842BDBM111842(US8623906, JHE-02-063B | US9174969, JHE-02-063B)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111856BDBM111856(US8623906, JF039 | US9174969, JF039)
Affinity DataIC50: 8.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111852BDBM111852(US8623906, JHE-02-035A | US9174969, JHE-02-035A)
Affinity DataIC50: 8.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111841BDBM111841(US8623906, JF025 | US9174969, JF025)
Affinity DataIC50: 8.20E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111823BDBM111823(BDBM111857 | US8623906, JHE-02-069 | US8623906, JH...)
Affinity DataIC50: 8.20E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111827BDBM111827(US8623906, JHE-02-032A | US9174969, JHE-02-032A)
Affinity DataIC50: 8.30E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111875BDBM111875(US8623906, JHE-02-020A | US9174969, JHE-02-020A)
Affinity DataIC50: 8.30E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111853BDBM111853(US8623906, JF022 | US9174969, JF022)
Affinity DataIC50: 8.40E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111848BDBM111848(US8623906, JF027 | US9174969, JF027)
Affinity DataIC50: 8.50E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111859BDBM111859(US8623906, JF040 | US9174969, JF040)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111877BDBM111877(US8623906, XW2-038E | US9174969, XW2-038E)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111849BDBM111849(US8623906, XW2-119 | US9174969, XW2-119)
Affinity DataIC50: 9.10E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111869BDBM111869(US8623906, JHE-02-010A | US9174969, JHE-02-010A)
Affinity DataIC50: 9.30E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111881BDBM111881(US8623906, JHE-01-169 | US9174969, JHE-01-169)
Affinity DataIC50: 9.60E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111840BDBM111840(US8623906, JHE-02-032B | US9174969, JHE-02-032B)
Affinity DataIC50: 9.90E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111861BDBM111861(US8623906, JF021 | US9174969, JF021)
Affinity DataIC50: 1.04E+4nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 111872BDBM111872(US8623906, XW2-031B | US9174969, XW2-031B)
Affinity DataIC50: 1.13E+4nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2014
Entry Details
US Patent

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