Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 6164
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112737BDBM112737(US8629141, 4)
Affinity DataKi:  1nM IC50: 15.6nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112736BDBM112736(US8629141, 2)
Affinity DataIC50: 41.8nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112742BDBM112742(US8629141, 9)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112773BDBM112773(US8629141, 43)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112748BDBM112748(US8629141, 15)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112755BDBM112755(US8629141, 25)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112754BDBM112754(US8629141, 21)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112753BDBM112753(US8629141, 20)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112759BDBM112759(US8629141, 29)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112758BDBM112758(US8629141, 28)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112757BDBM112757(US8629141, 27)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112763BDBM112763(US8629141, 33)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112762BDBM112762(US8629141, 32)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112761BDBM112761(US8629141, 31)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112768BDBM112768(US8629141, 38)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112767BDBM112767(US8629141, 37)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112766BDBM112766(US8629141, 36)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112771BDBM112771(US8629141, 41)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112770BDBM112770(US8629141, 40)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112769BDBM112769(US8629141, 39)
Affinity DataIC50: 100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112735BDBM112735(US8629141, 1)
Affinity DataIC50: 201nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112760BDBM112760(US8629141, 30)
Affinity DataIC50: 500nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112756BDBM112756(US8629141, 26)
Affinity DataIC50: 500nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112752BDBM112752(US8629141, 19)
Affinity DataIC50: 1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112740BDBM112740(US8629141, 7)
Affinity DataIC50: 1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112772BDBM112772(US8629141, 42)
Affinity DataIC50: 1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112739BDBM112739(US8629141, 6)
Affinity DataIC50: 1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112744BDBM112744(US8629141, 11)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112743BDBM112743(US8629141, 10)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112741BDBM112741(US8629141, 8)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112745BDBM112745(US8629141, 12)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112751BDBM112751(US8629141, 18)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112750BDBM112750(US8629141, 17)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112749BDBM112749(US8629141, 16)
Affinity DataIC50: 5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112764BDBM112764(US8629141, 34)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112747BDBM112747(US8629141, 14)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112746BDBM112746(US8629141, 13)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112765BDBM112765(US8629141, 35)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 112738BDBM112738(US8629141, 5)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent