Compile Data Set for Download or QSAR
Report error Found 174 Enz. Inhib. hit(s) with all data for entry = 6173
LigandChemical structure of BindingDB Monomer ID 113428BDBM113428(US8633204, 127)
Affinity DataIC50: 0.480nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50433038BDBM50433038(CHEMBL2375957 | US8633204, 299)
Affinity DataIC50: 0.686nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113443BDBM113443(US8633204, 146)
Affinity DataIC50: 0.731nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113420BDBM113420(US8633204, 115)
Affinity DataIC50: 0.75nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113542BDBM113542(US8633204, 276)
Affinity DataIC50: 0.788nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113434BDBM113434(US8633204, 137)
Affinity DataIC50: 0.989nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113441BDBM113441(US8633204, 144)
Affinity DataIC50: 1.01nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113437BDBM113437(US8633204, 140)
Affinity DataIC50: 1.03nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113479BDBM113479(US8633204, 191)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113455BDBM113455(US8633204, 165)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113453BDBM113453(US8633204, 163)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113544BDBM113544(US8633204, 278)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113448BDBM113448(US8633204, 158)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113535BDBM113535(US8633204, 265)
Affinity DataIC50: 1.43nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113551BDBM113551(US8633204, 288)
Affinity DataIC50: 1.44nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113417BDBM113417(US8633204, 108)
Affinity DataIC50: 1.57nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50433044BDBM50433044(CHEMBL2375963 | US8633204, 304)
Affinity DataIC50: 1.58nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113543BDBM113543(US8633204, 277)
Affinity DataIC50: 1.59nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113495BDBM113495(US8633204, 217)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113469BDBM113469(US8633204, 180)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113461BDBM113461(US8633204, 171)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113526BDBM113526(US8633204, 254)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113432BDBM113432(US8633204, 135)
Affinity DataIC50: 1.77nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113541BDBM113541(US8633204, 274)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113527BDBM113527(US8633204, 255)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113489BDBM113489(US8633204, 207)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113571BDBM113571(US8633204, 318)
Affinity DataIC50: 2.14nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113536BDBM113536(US8633204, 266)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113550BDBM113550(US8633204, 287)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113490BDBM113490(US8633204, 210)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113540BDBM113540(US8633204, 273)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113467BDBM113467(US8633204, 177)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113557BDBM113557(US8633204, 294)
Affinity DataIC50: 2.60nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113477BDBM113477(US8633204, 189)
Affinity DataIC50: 2.70nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113499BDBM113499(US8633204, 221)
Affinity DataIC50: 2.80nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113545BDBM113545(US8633204, 279)
Affinity DataIC50: 2.90nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50387590BDBM50387590(CHEMBL2057725 | US8633204, 111)
Affinity DataIC50: 2.96nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113433BDBM113433(US8633204, 136)
Affinity DataIC50: 3.08nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113528BDBM113528(US8633204, 256)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113568BDBM113568(US8633204, 315)
Affinity DataIC50: 3.11nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50433043BDBM50433043(CHEMBL2375961 | US8633204, 307)
Affinity DataIC50: 3.62nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113485BDBM113485(US8633204, 201)
Affinity DataIC50: 3.70nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50433045BDBM50433045(CHEMBL2375964 | US8633204, 303)
Affinity DataIC50: 3.87nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113532BDBM113532(US8633204, 260)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113546BDBM113546(US8633204, 280)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113533BDBM113533(US8633204, 261)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50433037BDBM50433037(CHEMBL2375956 | US8633204, 311)
Affinity DataIC50: 4.11nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113465BDBM113465(US8633204, 175)
Affinity DataIC50: 4.30nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113539BDBM113539(US8633204, 272)
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50387582BDBM50387582(CHEMBL2057736 | US8633204, 196)
Affinity DataIC50: 4.5nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

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