Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 6287
TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120748(US8703767, 8)
Affinity DataIC50: 33nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120741(US8703767, 1)
Affinity DataIC50: 45nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120748(US8703767, 8)
Affinity DataIC50: 47nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120741(US8703767, 1)
Affinity DataIC50: 79nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120743(US8703767, 3)
Affinity DataIC50: 126nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120742(US8703767, 2)
Affinity DataIC50: 187nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120743(US8703767, 3)
Affinity DataIC50: 230nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120744(US8703767, 4)
Affinity DataIC50: 263nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120747(US8703767, 7)
Affinity DataIC50: 287nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120747(US8703767, 7)
Affinity DataIC50: 518nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120742(US8703767, 2)
Affinity DataIC50: 562nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120752(US8703767, 12)
Affinity DataIC50: 829nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120749(US8703767, 9)
Affinity DataIC50: 1.27E+3nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120745(US8703767, 5)
Affinity DataIC50: 1.81E+3nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120744(US8703767, 4)
Affinity DataIC50: 3.77E+3nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120750(US8703767, 10)
Affinity DataIC50: 4.70E+3nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120751(US8703767, 11)
Affinity DataIC50: 1.44E+4nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120746(US8703767, 6)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent