Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 6329
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123462BDBM123462(US8741923, 35)
Affinity DataKi:  0.230nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123463BDBM123463(US8741923, 36)
Affinity DataKi:  0.490nM ΔG°:  -49.4kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123466BDBM123466(US8741923, 39)
Affinity DataKi:  0.600nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123457BDBM123457(US8741923, 16)
Affinity DataKi:  0.700nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123464BDBM123464(US8741923, 37)
Affinity DataKi:  0.75nM ΔG°:  -48.4kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123465BDBM123465(US8741923, 38)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123455BDBM123455(US8741923, 12)
Affinity DataKi:  0.800nM ΔG°:  -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123456BDBM123456(US8741923, 15)
Affinity DataKi:  1nM ΔG°:  -47.8kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123467BDBM123467(US8741923, 40)
Affinity DataKi:  1.10nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123453BDBM123453(US8741923, 10)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123459BDBM123459(US8741923, 24)
Affinity DataKi:  3nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123454BDBM123454(US8741923, 11)
Affinity DataKi:  4nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123461BDBM123461(US8741923, 27)
Affinity DataKi:  4.26nM ΔG°:  -44.4kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123449BDBM123449(US8741923, 1)
Affinity DataKi:  5nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123452BDBM123452(US8741923, 5)
Affinity DataKi:  5nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123451BDBM123451(US8741923, 4)
Affinity DataKi:  5nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123460BDBM123460(US8741923, 25)
Affinity DataKi:  11nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123450BDBM123450(US8741923, 3)
Affinity DataKi:  38nM ΔG°:  -39.4kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

US Patent
LigandChemical structure of BindingDB Monomer ID 123458BDBM123458(US8741923, 22)
Affinity DataKi:  164nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent