Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 6347
TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123867BDBM123867(US8748418, 12)
Affinity DataIC50: 5nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123862BDBM123862(US8748418, 6)
Affinity DataIC50: 11nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123857BDBM123857(US8748418, 1)
Affinity DataIC50: 24nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123869BDBM123869(US8748418, 14)
Affinity DataIC50: 28nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123862BDBM123862(US8748418, 6)
Affinity DataIC50: 30nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123864BDBM123864(US8748418, 8)
Affinity DataIC50: 30nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123858BDBM123858(US8748418, 2)
Affinity DataIC50: 35nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123870BDBM123870(US8748418, 15)
Affinity DataIC50: 40nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123858BDBM123858(US8748418, 2)
Affinity DataIC50: 40nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123870BDBM123870(US8748418, 15)
Affinity DataIC50: 58nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123857BDBM123857(US8748418, 1)
Affinity DataIC50: 70nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123869BDBM123869(US8748418, 14)
Affinity DataIC50: 71nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123859BDBM123859(US8748418, 3)
Affinity DataIC50: 72nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123860BDBM123860(US8748418, 4)
Affinity DataIC50: 73nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123864BDBM123864(US8748418, 8)
Affinity DataIC50: 90nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123868BDBM123868(US8748418, 21 | US8748418, 13)
Affinity DataIC50: 95nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123867BDBM123867(US8748418, 12)
Affinity DataIC50: 120nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123871BDBM123871(US8748418, 16)
Affinity DataIC50: 120nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123871BDBM123871(US8748418, 16)
Affinity DataIC50: 133nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123863BDBM123863(US8748418, 7)
Affinity DataIC50: 170nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123875BDBM123875(US8748418, 20)
Affinity DataIC50: 170nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123873BDBM123873(US8748418, 18)
Affinity DataIC50: 240nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123868BDBM123868(US8748418, 21 | US8748418, 13)
Affinity DataIC50: 310nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123874BDBM123874(US8748418, 19)
Affinity DataIC50: 310nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123863BDBM123863(US8748418, 7)
Affinity DataIC50: 310nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123872BDBM123872(US8748418, 17)
Affinity DataIC50: 320nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123877BDBM123877(US8748418, 22)
Affinity DataIC50: 370nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123872BDBM123872(US8748418, 17)
Affinity DataIC50: 400nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123860BDBM123860(US8748418, 4)
Affinity DataIC50: 400nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123880BDBM123880(US8748418, 25)
Affinity DataIC50: 410nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123878BDBM123878(US8748418, 23)
Affinity DataIC50: 440nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123873BDBM123873(US8748418, 18)
Affinity DataIC50: 530nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123859BDBM123859(US8748418, 3)
Affinity DataIC50: 580nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123865BDBM123865(US8748418, 9)
Affinity DataIC50: 650nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123866BDBM123866(US8748418, 10)
Affinity DataIC50: 700nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123866BDBM123866(US8748418, 10)
Affinity DataIC50: 910nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123879BDBM123879(US8748418, 24)
Affinity DataIC50: 940nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123879BDBM123879(US8748418, 24)
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123878BDBM123878(US8748418, 23)
Affinity DataIC50: 1.36E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123861BDBM123861(US8748418, 5)
Affinity DataIC50: 1.48E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123883BDBM123883(US8748418, 28)
Affinity DataIC50: 1.49E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123880BDBM123880(US8748418, 25)
Affinity DataIC50: 1.63E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123877BDBM123877(US8748418, 22)
Affinity DataIC50: 1.77E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123881BDBM123881(US8748418, 26)
Affinity DataIC50: 1.90E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123875BDBM123875(US8748418, 20)
Affinity DataIC50: 1.90E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123865BDBM123865(US8748418, 9)
Affinity DataIC50: 2.10E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123861BDBM123861(US8748418, 5)
Affinity DataIC50: 2.40E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123868BDBM123868(US8748418, 21 | US8748418, 13)
Affinity DataIC50: 2.81E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123881BDBM123881(US8748418, 26)
Affinity DataIC50: 3.89E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 123874BDBM123874(US8748418, 19)
Affinity DataIC50: 4.16E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

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